Lab Series #2: Baylor Charles A. Sammons Cancer Center

Your donations allow SAA to provide funding to some of the world’s most renowned cancer institutions. This is the second in a series featuring the SAA LABS that our beneficiaries have named in honor of the efforts of Swim Across America.

1785-4X6This month, we are profiling the Swim Across America Innovative Clinical Trials Center (ICTC) at Baylor Charles A. Sammons Cancer Center at Dallas. The trials center was named for SAA in 2013 and features some treatments that can’t be found anywhere else in the country. Dr. Alan M. Miller, MD, PhD and Director of the Baylor Charles A. Sammons Cancer Center and Carlos Becerra, MD were kind enough to answer some of our questions. 

What does the ICTC mean to the doctors and patients that use it?

The Swim Across America Innovative Clinical Trials Center (ICTC) at Baylor University Medical Center is a clinical facility where patients come to receive treatments that are available at only a few specialized centers in the country or may only be available at the ICTC.

These trials provide options for patients whose cancer has resisted standard therapies.  Many fall into the category, Phase 1 trials. These require a specialized staff with experience in treating patients with new therapies.

What kind of cancer research is being done in the ICTC?

In the past few years, the physicians and staff of the Swim Across America ICTC have participated in some of the most exciting studies using precision medicine and immunotherapy. Precision medicine involves analyzing the genes of the cancer and applying drugs that specifically target abnormalities in the cancer cells that are not in the individuals’ normal tissue. Immunotherapy harnesses the body’s own immune system to help attack the cancer.1794

What plans are in store for 2016 and beyond?

An exciting trial starting in 2016 involves the use of a dendritic cell vaccine to treat pancreatic cancer.  Dendritic cells are cells of the immune system that identify abnormal cells like a bacteria or a cancer cell and then call in other components of the immune system to attack the invader. This dendritic cell vaccine was developed in the laboratory of the Baylor Institute for Immunology Research and is only available at the ICTC.

“Thanks to the funding from Swim Across America we have been able to explore new and very encouraging therapeutic targets for otherwise deadly diseases such as pancreatic cancer or refractory colon cancer and have been able to provide patients with novel therapies that would not otherwise be possible. We have taken discoveries from the lab of our scientists and tested the concept in the clinic thanks to the support of SAA, an example of translational work done within the walls of Baylor University Medical Center.” – Carlos Becerra, MD

For further information about the Swim Across America ICTC, please view the following video (the ICTC is featured at 3:38) or see more info on all the studies to the trials currently going on here.

Fun and Inspiration at SMAC Out Cancer

The fourth annual SMAC Out Cancer Pool Swim was another great success, raising over $84K and counting at the San Mateo Athletic. This year’s swim featured 11 fun events, seven Olympians, and honored multiple heroes in the fight against cancer.

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The four-year total raised by SMAC Out Cancer stands at an incredible $296K to fund cancer research at beneficiaries UCSF Benioff Children’s Hospital and Children’s Hospital Oakland Research Institute. Congrats to event director Diana Thomas for putting together another great event this year.

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The 2016 swim was named in memory of Jim Keller, who lost his battle with cancer in January. Keller was regarded as a brilliant and caring man that was a huge supporter of the San Mateo Athletic Club. He’s pictured here with Olympian Heather Petri in 2015.

The impact of the event was evident when the Olympians got to meet Wills Levy, a young hero that saved his brother’s life with a bone marrow transplant. The incredible and moving story of his younger brother Andrew’s battle with a rare and deadly cancer and unlikely recovery is featured in this emotional New York Times Magazine article. Olympians at the event included: Craig Beardsley, Mike Bruner, Susan Heon Preston, Roque Santos, Glenn Mills, Ellen Estes and Christine Magnuson.

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Wills Levy (center) with Olympians at SMAC

The event features fun events not usually associated with SAA pool swims including an aqua aerobics boot camp, and out-of-water fitness challenge and a dance party. Check out the whole photo library to see all the breathtaking images from the event. If you’re interested in starting a pool swim in your community, learn more here.

SAA Impact in Seattle

Seattle Cancer Care Alliance, the beneficiary of the SAA – Seattle swim has released their latest Impact Report. This report details how the Swim Across America Cellular Therapy Laboratory is responsible for all therapeutic cell processing at SCCA. Funds from SAA – Seattle also support the Pancreas Cancer Specialty Clinic. You can download the Seattle SAA Impact Report to learn more.22010282331_14ae7bfd0f_z

From the Swim Across America Cellular Therapy Laboratory:

“Over the past six years, SAA – Seattle funds have supported cell-based immunotherapy trials aimed at increasing graft versus cancer effect and reducing Graft Versus Host Disease. Those studies and follow-on protocols to refine the technology and incorporate more donor options are continuing. In addition, SAA – Seattle funds have prepared us to process cells for the Chimeric Antigen T Cell Receptor (CAR T) clinical trials.

The first CAR T protocol for SCCA patients is producing extraordinary results in which cancer patients that had been unresponsive to or relapsed from other therapies are experiencing complete remissions…we expect at least 3 more CAR T trials to start and SAAS funding will allow us to train staff and test processes to build the much needed capacity to support this rapidly expanding work.”

From the Pancreas Cancer Speciality Clinic:

“The STTR Molecular Diagnostics Repository SAA – Seattle is supporting evaluates the genomic, metabolomic, proteomic and immunological profiles of pancreas cancer, helping to create and share information and access samples more quickly and affordably…SAAS will fund 2-3 researchers’ pilot studies to advance the science, hopefully paving the way for future full scale proposals. We are grateful to the SAAS for its continued support of the Pancreas Program.”

SAA on the Scene

Members of the Swim Across America family are active in their communities. SAA on the Scene shares stories from the “dry side” of our events where the SAA mission to make waves to defeat cancer is honored and recognized. Feel free to send submissions for future posts here.

Alliance for Cancer Gene Therapy (ACGT) Discovery Celebration
Harvard Club (New York) – April 14 

Greenwich-Stamford co-chairs Michele Graham and Lorrie Lorenz, and SAA Director of Events Craig Beardsley were in attendance to learn how dollars granted to ACGT are defeating cancer.

Swim Across America AYA Lounge One-Year Anniversary Celebration
Moffitt Cancer Center (Tampa) – April 26

SAA – Tampa Event Director Rob Shapiro and committee members Alicia Reyes-Shapiro, Tony Scicchitano, Janice Scicchitano and Olivia Fridgen participated in the one-year anniversary of the Adolescent and Young Adult Lounge opening. We profiled AYA in our lab series profile.

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SAA – Long Island Sound Swim Kickoff Event
Larchmont Yacht Club – April 27

The 24th annual Long Island Sound Open Water Swim Kickoff event took place on April 27th. Beneficiary representatives from Memorial Sloan-Kettering, Columbia University Medical Center and Cancer Support Team attended the event. Dr. Jedd Wolchok, MD PhD (of MSK) and Dr. Andrew Kung, MD PhD (of CUMC) spoke at the event sharing breakthroughs being made to defeat cancer in their labs.

2016 Larchmont Kickoff

Craig Beardsley (SAA Director of Events), Jean Fufidio, Dr. Jedd Wolchok, MD PhD, Dr. Sadna Budhu PhD, Tony Sibio (SAA – LIS chair and event director)

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Robyn Gartrell MD, Dr. Andrew Kung, MD PhD, Lucille Winton, Katie Shields, Dr. Jedd Wolchok, MD PhD, Dr. Sadna Budhu PhD, Dr. James Garvin MD PhD, Tony Sibio (SAA – Larchmont chair and event director)

Boston Team Relay Challenge Recap

The 5th Annual Boston Team Relay Challenge at Harvard’s Blodgett Pool took place on April 9. Eleven teams swam and had fun raising over $70,000 for Dana-Farber and Mass General Hospital for Children Cancer Center. The relay swim challenges each team to swim as far as they can collectively over 2 hours. Teams with higher fundraising leading into the event day get additional yardage added to their total to support their efforts.

The top team overall was the Gator & Apex team, a club team in the greater Boston area. Not only did they swim the farthest, they raised the most coming in at almost $20,000! Congrats to Gator & Apex team as well as Kerry Swords for being top individual fundraiser for the event.

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Pool Swims Across America

In Pool Swims Across America, we feature local pool swims that raise awareness for cancer research. If you’re interested in getting your local swim team or pool involved, learn more here.

The Cheshire Pool Swim to Fight Cancer raised $6,400 on April 23 in Cheshire, CT. A big round of applause for high school junior Kevin Erickson for organizing and to the members of the Yale men’s swim team for coming by to participate in the great cause. Great work by everyone that came out to Cheshire Community Pool to make waves to defeat cancer!

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The inaugural Belleair Country Club Pool Swim took place on May 1 at Belleair Country Club in Belleair, Fl. The BCC Breakers did a great job hitting their fundraising goal in their first year, raising $4,030 to contribute to the Moffitt Cancer Center in Tampa!

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SAA Tee Time in Central Florida

The first event of the calendar year featuring Swim Across America as an official charity of the 7-Eleven Franchise Owners Association took place on April 6 in Orlando. The weather was beautiful for the 7-Eleven Central Florida Franchise Owners Association Charity Golf Tournament to benefit Swim Across America (Tampa) and Moffitt Cancer Center.

The SAA family was well represented with Craig Beardsley, Craig Cordell (SAA – Tampa), Alison Pease (SAA – Chicago), Olympian Rowdy Gaines, Susan Davis (Nestlé), and Mark Gramlich (Kellogg’s) in attendance. The tournament successfully raised $20,711.00 for the SAA – Tampa which benefits the Tampa Moffitt Cancer Center.

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SAA Lab Doctor speaks to Montclair Pool Swim Students

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The 3rd Annual Swim to Win Against Cancer Pool Swim took place earlier this year in Montclair, N.J., featuring student-athletes from Montclair High School and Newark Academy.

The students participating in the annual swim challenge were lucky enough to meet and participate in a Q&A session with Dr. Taha Merghoub, visiting from an SAA beneficiary, Memorial Sloan-Kettering Cancer Center. Dr. Merghoub is also the Co- Director of the Ludwig Collaborative and Swim Across America Lab at MSK. Sarah Dillon Soden, Associate Director, Annual Giving at MSK also spoke at the event.

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Dr. Taha Merghoub of Memorial Sloan-Kettering Cancer Center

The students learned how the nearly $50,000 they’ve raised over the last three years at their pool swim challenge has helped fund the SAA Lab where Dr. Merghoub investigates the pathogenesis and treatment of melanoma.

A special thanks goes out to Montclair High School Swim Coach Ed Koenigsfest and Newark Academy Swim Coach Billy Blomn for supporting SAA and creating a great pool swim challenge where the competition focuses on a common goal.

Learn more about starting an SAA Pool Swim in your community here.

Check Presentation for SAA – San Francisco

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(L-R) Mike Bruner (Olympian), Dr. Robert Goldsby (UCSF beneficiary), Susan Helmrich (SAA-SF Co-Event Director), Dr. Julie Saba (UCSF Oakland beneficiary), Heather Petri (Olympian and Honorary Chair SF-SAA) and Anthony DuComb (SAA-SF Co-Event Director).

On March 14, members of the Swim Across America – San Francisco family took part in a special check presentation at the Children’s Hospital Oakland Research Institute.

 

San Francisco Co-Event Directors Susan Helmrich and Anthony DuComb represented Swim Across America along with Olympians Mike Bruner and Heather Petri as they presented a $450,000 check to UCSF Benioff Children’s Hospitals. Dr. Robert Goldsby  (UCSF) and Dr. Julie Saba (UCSF Oakland) both spoke at the event and thanked all the SAA swimmers, kayakers, volunteers, olympians and donors for their contributions to defeat pediatric cancer.

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Event Flyer
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(L-R) DuComb, Helmrich, Dr. Saba, Dr. Goldsby

Lab Series #1: Moffitt Cancer Center

Your donations allow SAA to provide funding to some of the world’s most renowned cancer institutions. This is the first in a series featuring the SAA LABS that our beneficiaries have named in honor of the efforts of Swim Across America.

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Swim Across America Adolescent & Young Adult Lounge

This month, we are profiling the Swim Across America Adolescent and Young Adult Lounge at the Moffitt Cancer Center in Tampa. The ribbon-cutting ceremony took place in April 2015 (featuring Tampa Bay Open Water Swim Event Director Rob Shapiro, former SAA CEO Janel Jorgensen-McArdle and current SAA CEO Rob Butcher). The SAA AYA Lounge is used by the approximately 100 young adult cancer patients at the hospital every day. Olivia Fridgen, AYA and LATTE Program Coordinator at Moffitt provided this insight.

How has the reception been to the SAA AYA Lounge by patients?
The reception from patients has been amazing. The corkboard wall on the lounge shows patient artwork, the white board has encouragement from patient to patient and the lounge journal has pages and pages of thoughts and inspirational words. It has been a respite for inpatients who need a change of scenery, as a place to spend time with their family and friends who come to visit and a great spot for the AYA (Adolescent and Young Adults) Program to host events and support groups.

Since the SAA AYA Lounge is different from  other research-based SAA Labs, what interesting facts can you pass along?
We are the 1st AYA Lounge in Florida, the 3rd in the country. We are also unique because our lounge provides physical space not only for our inpatients but our outpatients as well. Some of the traditional lounges are built in conjunction with inpatient units and therefore are not accessible to outpatients. Another unique mention is that our Moffitt AYA Patients actually designed the entire space – they picked out color schemes, fabrics, flooring and lighting so that we were confident our lounge was hitting the mark and what AYA patients would actually want in a space.

Do patients get treatment in the SAA AYA Lounge?
No, the lounge is a place to get away from the hustle bustle of the hospital life. The Lounge has the latest gaming systems, comfy couches, white boards, board games and art supplies. The inpatient floors of the hospital, where admitted patients would receive treatment, is steps away which provides convenience and access to the lounge.


 

How much did it cost to build the SAA AYA Lounge?
SAA has donated nearly $140,000 to the AYA program over the years and monies from the 2014 race were specifically designated to the creation of the SAA AYA Lounge.

Does the AYA Group anticipate this to be a trend in hospital systems moving forward?
Yes, organizations like Teen Cancer America are working with AYA Programs across the country to fund and offer physical spaces in hospitals for young cancer patients.

Why is it important for Moffitt and other hospitals to have a lounge for adolescent and young adults?
Adolescent and Young Adult patients feel like they are the only 20- or 30-year-old in the entire hospital. While we know that isn’t true, each patient is seen in their respective clinic (for example, if you have breast cancer you’re seen in the Breast Clinic, if you have Lung Cancer you’re seen in Thoracic, etc.), so they never get the chance to run into one another. The Lounge provides a space where Young Adult cancer patients can actually meet another young person with cancer. Because it’s in a communal space, it’s less awkward, more organic and can reduce the feelings of isolation many AYAs feel, which is important to their psychosocial state of mind and also can create lasting friendships. Many of our patients say that family and friends are extremely supportive, but no one quite “gets it” like another young cancer patient.