Lab Series #3: Rush University Cancer Center

Your donations allow SAA to provide funding to some of the world’s most renowned cancer institutions. This is the third in a series featuring the SAA LABS that our beneficiaries have named in honor of the efforts of Swim Across America.

This month, we are profiling the Swim Across America Laboratory for Cancer Research at Rush University Medical Center. This lab, and a Patient Procedure Suite, were named for SAA in 2015 after more than $1 million was raised by SAA since 2011.

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Each year, Rush University Medical Center runs an internal, peer-reviewed process to distribute the funds from SAA – Chicago. Rush researchers submitted more than 20 proposals for consideration for the proceeds from last year’s Chicago events, which included the open water swim at Ohio Street Beach and the 2nd Swim Across Lake Michigan. Four research projects will be funded from 2015 and the awards have been made to support projects focused on a variety of treatment disciplines that impact patients with breast, colon, liver, and lung cancers, among others.

Kevin Gray, Director of Development at Rush University Medical Center was kind enough to answer some of our questions.

Can you shed some light on the cancer research being done in the SAA lab??

The cancer research being done with SAA funds varies from breast, gastro, lung and other. Dr. Jeff Borgia’s lab, which was named the Swim Across America Laboratory for Cancer Research, focuses on two areas: 1) Identifying a genetic marker within specific proteins that determine a person’s likelihood that they have or could develop lung cancer. And 2) fine-tuning a blood test – finger prick – that could be used in all primary care offices, but specifically in underserved communities and areas with high incidence of lung disease.

What kind of grants have been acquired through the research?

There have been more than two dozen grants from various sources that continue to help all investigators during the timeframe of the SAA relationship. Most notable, two investigators, Drs. Carl Maki and Amanda Marzo, have leveraged SAA dollars to garner NIH funding. Dr. Marzo received $425,000 earlier this month and Dr. Maki received $375,000 last year.

What exciting plans does Rush have for 2016 and beyond?

The most exciting plans are technology and equipment investment. A computer-based initiative called bioinformatics and a biorepository will take Rush to the next level in terms of productivity and competitiveness. Bioinformatics is the ability, through extremely fast computers, to process an enormous amount of data in an extremely short time. Information that used to take weeks now can be processed in days or hours. It will be paired with the biorepository, which is housed in the SAA lab, which can process and store large amounts of tissue or blood samples for study. This enables the investigators to work faster and more efficiently, revealing new answers and results that potentially lead to a treatment or cure.

What does the lab mean to Rush?

It means a myriad of things:  1) It enables Rush to conduct meaningful research with an almost instant impact on patients. 2) It attracts the best and the brightest to Rush as the institution is tackling cutting-edge work. 3) It makes Rush a stronger academic institution as tomorrow’s doctors, nurses and other medical professionals get to work side-by-side with the best And 4) It puts Rush and those with SAA backing in a position to find the best solutions for new treatments and possibly a cure.

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2015 Swim Across America Lab Dedication

Swim Across America on Snapchat

We’re excited to have members of the SAA family take turns running the SAA account on Snapchat. We have highlights from Greenwich and Boston for you to catch up on. If you haven’t started following – do so now at snapchat.com/add/saaswim or use this snap code:
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Greenwich Highlights (guest user – Brooke Lorenz)

SAA Greenwich 2016 from Swim Across America on Vimeo.

Boston Highlights (guest users – Olypmians Kristy Kowal and Heather Petri)

SAA on the Scene

Members of the Swim Across America family are active in their communities. SAA on the Scene shares stories from the “dry side” of our events where the SAA mission to make waves to defeat cancer is honored and recognized. Feel free to send submissions for future posts here.

Gerry Oakes Swim Across America Lifetime Achievement Award celebration
May 26th 

Thank you to Gerry Oakes for nearly 20 years of service. It is our privilege to recognize you with a Lifetime Achievement Award!

 

Nantucket Day Celebration
Rose & Crown, Nantucket, May 11th

In the annual Nantucket Day celebration, the event committee was able to get 25 sign-ups at the event and had some good social media buzz going in the community.

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L-R: Jim Pignato (Co-Event Director), Stacey Williams (SAA-Nantucket Volunteer), Jill Roethke (Co-Event Director), Kate Bartleman (Nantucket Cottage Hospital), Kristen Dussault (SAA-Nantucket Committee Member), Charlene Thurston (PASCON), Beth Moyer (Nantucket Cottage Hospital) and Ginnia Faria (PASCON).

Swim Across America Visit to beneficiary Moffitt Cancer Center
Tampa, May 2oth

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Rob Butcher, Amy Krakauer, Angie Lankton and family, Dr. Shari Pilon-Thomas, Megan Melgaard, Michael Jorgensen, Ryan Baucom, Eric Wunderlich, Javed Saleemi and Craig Cordell.

 

San Diego 7-Eleven FOA Golf Tournament
Tampa, May 12th

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Mark Gramlich, Susan Davis, Olympian Andrea Dickson, Olympian Ryan Berube, Diana Thomas, Falon Lesczcynski

SAA Family Tree (June)

SAA Family Tree is a monthly focus on stories that display the impact all the members of the Swim Across America family have both locally and nationally. If you have a story or link you’d like to share, please send here.

  • An incredible New York Times story on the Levy family featuring Wills Levy, a bone marrow transplant donor that helped save his brother Andrew’s life. Wills participated at the SAA – SMAC Out Cancer Pool Swim in May.
  • A great feature on the 10th anniversary of the Greenwich-Stamford swim featuring proud participants Craig Lawrence, Victoria Dinkel and the Bass family.
  • SAA beneficiary Memorial Sloan Kettering and its pediatrics department was the  focus of a popular ‘Humans of New York’ series that raised a lot of awareness and funds for MSK.
  • Emily Crabtree of SAA – Chicago and the swim were highlighted in the Rush University Medical Center annual report.
  • Greenwich-Stamford swimmer Julia Neri was featured locally for being named valedictorian among other notable achievements.
  • Swim Across America was the Event Spotlight feature in SwimSwam Magazine’s Olympics Preview Issue. Pick up a copy and see how great the 4-page spread turned out!13245263_10153490105146176_5270864362521739117_n

Lab Series #2: Baylor Charles A. Sammons Cancer Center

Your donations allow SAA to provide funding to some of the world’s most renowned cancer institutions. This is the second in a series featuring the SAA LABS that our beneficiaries have named in honor of the efforts of Swim Across America.

1785-4X6This month, we are profiling the Swim Across America Innovative Clinical Trials Center (ICTC) at Baylor Charles A. Sammons Cancer Center at Dallas. The trials center was named for SAA in 2013 and features some treatments that can’t be found anywhere else in the country. Dr. Alan M. Miller, MD, PhD and Director of the Baylor Charles A. Sammons Cancer Center and Carlos Becerra, MD were kind enough to answer some of our questions. 

What does the ICTC mean to the doctors and patients that use it?

The Swim Across America Innovative Clinical Trials Center (ICTC) at Baylor University Medical Center is a clinical facility where patients come to receive treatments that are available at only a few specialized centers in the country or may only be available at the ICTC.

These trials provide options for patients whose cancer has resisted standard therapies.  Many fall into the category, Phase 1 trials. These require a specialized staff with experience in treating patients with new therapies.

What kind of cancer research is being done in the ICTC?

In the past few years, the physicians and staff of the Swim Across America ICTC have participated in some of the most exciting studies using precision medicine and immunotherapy. Precision medicine involves analyzing the genes of the cancer and applying drugs that specifically target abnormalities in the cancer cells that are not in the individuals’ normal tissue. Immunotherapy harnesses the body’s own immune system to help attack the cancer.1794

What plans are in store for 2016 and beyond?

An exciting trial starting in 2016 involves the use of a dendritic cell vaccine to treat pancreatic cancer.  Dendritic cells are cells of the immune system that identify abnormal cells like a bacteria or a cancer cell and then call in other components of the immune system to attack the invader. This dendritic cell vaccine was developed in the laboratory of the Baylor Institute for Immunology Research and is only available at the ICTC.

“Thanks to the funding from Swim Across America we have been able to explore new and very encouraging therapeutic targets for otherwise deadly diseases such as pancreatic cancer or refractory colon cancer and have been able to provide patients with novel therapies that would not otherwise be possible. We have taken discoveries from the lab of our scientists and tested the concept in the clinic thanks to the support of SAA, an example of translational work done within the walls of Baylor University Medical Center.” – Carlos Becerra, MD

For further information about the Swim Across America ICTC, please view the following video (the ICTC is featured at 3:38) or see more info on all the studies to the trials currently going on here.

Fun and Inspiration at SMAC Out Cancer

The fourth annual SMAC Out Cancer Pool Swim was another great success, raising over $84K and counting at the San Mateo Athletic. This year’s swim featured 11 fun events, seven Olympians, and honored multiple heroes in the fight against cancer.

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The four-year total raised by SMAC Out Cancer stands at an incredible $296K to fund cancer research at beneficiaries UCSF Benioff Children’s Hospital and Children’s Hospital Oakland Research Institute. Congrats to event director Diana Thomas for putting together another great event this year.

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The 2016 swim was named in memory of Jim Keller, who lost his battle with cancer in January. Keller was regarded as a brilliant and caring man that was a huge supporter of the San Mateo Athletic Club. He’s pictured here with Olympian Heather Petri in 2015.

The impact of the event was evident when the Olympians got to meet Wills Levy, a young hero that saved his brother’s life with a bone marrow transplant. The incredible and moving story of his younger brother Andrew’s battle with a rare and deadly cancer and unlikely recovery is featured in this emotional New York Times Magazine article. Olympians at the event included: Craig Beardsley, Mike Bruner, Susan Heon Preston, Roque Santos, Glenn Mills, Ellen Estes and Christine Magnuson.

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Wills Levy (center) with Olympians at SMAC

The event features fun events not usually associated with SAA pool swims including an aqua aerobics boot camp, and out-of-water fitness challenge and a dance party. Check out the whole photo library to see all the breathtaking images from the event. If you’re interested in starting a pool swim in your community, learn more here.

SAA Impact in Seattle

Seattle Cancer Care Alliance, the beneficiary of the SAA – Seattle swim has released their latest Impact Report. This report details how the Swim Across America Cellular Therapy Laboratory is responsible for all therapeutic cell processing at SCCA. Funds from SAA – Seattle also support the Pancreas Cancer Specialty Clinic. You can download the Seattle SAA Impact Report to learn more.22010282331_14ae7bfd0f_z

From the Swim Across America Cellular Therapy Laboratory:

“Over the past six years, SAA – Seattle funds have supported cell-based immunotherapy trials aimed at increasing graft versus cancer effect and reducing Graft Versus Host Disease. Those studies and follow-on protocols to refine the technology and incorporate more donor options are continuing. In addition, SAA – Seattle funds have prepared us to process cells for the Chimeric Antigen T Cell Receptor (CAR T) clinical trials.

The first CAR T protocol for SCCA patients is producing extraordinary results in which cancer patients that had been unresponsive to or relapsed from other therapies are experiencing complete remissions…we expect at least 3 more CAR T trials to start and SAAS funding will allow us to train staff and test processes to build the much needed capacity to support this rapidly expanding work.”

From the Pancreas Cancer Speciality Clinic:

“The STTR Molecular Diagnostics Repository SAA – Seattle is supporting evaluates the genomic, metabolomic, proteomic and immunological profiles of pancreas cancer, helping to create and share information and access samples more quickly and affordably…SAAS will fund 2-3 researchers’ pilot studies to advance the science, hopefully paving the way for future full scale proposals. We are grateful to the SAAS for its continued support of the Pancreas Program.”

SAA on the Scene

Members of the Swim Across America family are active in their communities. SAA on the Scene shares stories from the “dry side” of our events where the SAA mission to make waves to defeat cancer is honored and recognized. Feel free to send submissions for future posts here.

Alliance for Cancer Gene Therapy (ACGT) Discovery Celebration
Harvard Club (New York) – April 14 

Greenwich-Stamford co-chairs Michele Graham and Lorrie Lorenz, and SAA Director of Events Craig Beardsley were in attendance to learn how dollars granted to ACGT are defeating cancer.

Swim Across America AYA Lounge One-Year Anniversary Celebration
Moffitt Cancer Center (Tampa) – April 26

SAA – Tampa Event Director Rob Shapiro and committee members Alicia Reyes-Shapiro, Tony Scicchitano, Janice Scicchitano and Olivia Fridgen participated in the one-year anniversary of the Adolescent and Young Adult Lounge opening. We profiled AYA in our lab series profile.

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SAA – Long Island Sound Swim Kickoff Event
Larchmont Yacht Club – April 27

The 24th annual Long Island Sound Open Water Swim Kickoff event took place on April 27th. Beneficiary representatives from Memorial Sloan-Kettering, Columbia University Medical Center and Cancer Support Team attended the event. Dr. Jedd Wolchok, MD PhD (of MSK) and Dr. Andrew Kung, MD PhD (of CUMC) spoke at the event sharing breakthroughs being made to defeat cancer in their labs.

2016 Larchmont Kickoff

Craig Beardsley (SAA Director of Events), Jean Fufidio, Dr. Jedd Wolchok, MD PhD, Dr. Sadna Budhu PhD, Tony Sibio (SAA – LIS chair and event director)

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Robyn Gartrell MD, Dr. Andrew Kung, MD PhD, Lucille Winton, Katie Shields, Dr. Jedd Wolchok, MD PhD, Dr. Sadna Budhu PhD, Dr. James Garvin MD PhD, Tony Sibio (SAA – Larchmont chair and event director)

Boston Team Relay Challenge Recap

The 5th Annual Boston Team Relay Challenge at Harvard’s Blodgett Pool took place on April 9. Eleven teams swam and had fun raising over $70,000 for Dana-Farber and Mass General Hospital for Children Cancer Center. The relay swim challenges each team to swim as far as they can collectively over 2 hours. Teams with higher fundraising leading into the event day get additional yardage added to their total to support their efforts.

The top team overall was the Gator & Apex team, a club team in the greater Boston area. Not only did they swim the farthest, they raised the most coming in at almost $20,000! Congrats to Gator & Apex team as well as Kerry Swords for being top individual fundraiser for the event.

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