Preliminary findings from the clinical trial are hopeful and show the promise of cell therapy for treating incurable conditions.
“The CAR-T platform has revolutionized how we think about treating patients with cancer, but solid tumors like glioblastoma have remained challenging to treat because not all cancer cells are exactly alike and cells within the tumor vary. Our approach combines two forms of therapy, allowing us to treat glioblastoma in a broader, potentially more effective way.” said Bryan Choi, MD, PhD, neurosurgeon and associate director of the Center for Brain Tumor Immunology and Immunotherapy, Cellular Immunotherapy Program, Mass General Cancer Center and Department of Neurosurgery.
MRI results from a glioblastoma clinical trial that received initial grant funding from Swim Across America – Boston. The scans show tumor size before infusion (day -7) and after infusion (day 5).
Days after a single treatment, the three patients experienced dramatic reductions in their tumors, with one patient achieving near-complete tumor regression.
MRI scans conducted before and after treatment showed initial regression in tumor size. In time, the researchers observed tumor progression in these patients, but given the strategy’s promising preliminary results, the team will pursue strategies to extend the durability of response.
Dr. Choi expressed gratitude for the Swim Across America – Boston grant that made this research possible. Dr. Choi’s lab also receives funding from Swim Across America – Nantucket.
“Swim Across America directly supports my laboratory, which is dedicated to developing novel experimental immune therapies for patients with brain cancer. SAA funded a critical step in the early stage of discovery, allowing us to take on high risk projects that otherwise might not be possible.” said Dr. Choi.
“Without this type of support, my lab would not be able to develop or advance new therapies toward clinical studies like the one published here.”
Swim Across America – Boston and Swim Across America – Nantucket leadership teams visited Dr. Choi at Mass General Cancer Center in March 2023, just one month before the clinical trial was launched. During the visit, SAA leaders were treated to an informative presentation and lab tour from Dr. Choi.
During the tour, Janel Jorgensen McArdle, Chief Operating Officer of Swim Across America, pointed out that Dr. Choi’s research falls in the “sweet spot” of the high risk, high reward research that Swim Across America is pursuing.
“This promising research aligns perfectly with the opportunities that Swim Across America seeks to support. We are excited that SAA funding could help accelerate (this research) to patient trials.”
In March 2023, leaders from Swim Across America – Boston and Swim Across America – Nantucket visited Dr. Choi’s research lab at Mass General Cancer Center. Pictured: Michele Fox, Patty Gienke, Bob Hackett, Liam Hackett, Steven Laduzinski, Jamie Mannion, Janel Jorgensen McArdle, Alex Meyer, Rick Osterberg, Shep Perkins, Jill Roethke, Mike Ryan, Jessica Stokes, Kitty Tetreault.
Swim Across America’s grant agreement with beneficiaries, such as Mass General Cancer Center, requires that 100% of an SAA grant must be spent on approved research and clinical trial programs. Since 1987, SAA has granted over $100M to innovative and otherwise unfunded ideas so that the time of oncologists is protected to make progress and develop new treatments.
Read or watch local stories featuring the Swim Across America-Houston community to learn about their impact. Learn more about the event and beneficiary, MD Anderson Cancer Center, at swimacrossamerica.org/houston.
Read or watch local stories featuring the Swim Across America-San Francisco community to learn about their impact. Learn more about the event and beneficiary, UCSF Benioff Children’s Hospitals (Oakland and San Francisco), at swimacrossamerica.org/sanfrancisco.
Sarah Thomas is Believed to be the First Swimmer to Complete the Swim of the Entire Length of Lake Mead
LAS VEGAS, October 7, 2023 – On October 7, 2023, ultra marathon swimmer Sarah Thomas set another world record with a monumental swim that no other swimmer has ever attempted. Sarah completed a 47.5-mile swim of the entire length of Lake Mead – from the Colorado River to the Hoover Dam (distance pending ratification). The swim took her 26 hours, 45 minutes and 45 seconds (26:45:45) to complete. Sarah, a breast cancer survivor, took on this swim not just to break another world record, but to help make waves in the fight against cancer and to raise critical funds for cancer research with Swim Across America.
“The water was a balmy 78 on the surface and around 75 degrees in the swimming depth. I’m a cold water swimmer, so this was a bit warmer than I’m used to, but it ended up being lovely,” said Sarah Thomas. “I didn’t run into very many obstacles, except something wrapped around my arm at one point, but for the most part, the swim was really great! I’m so excited to be able to accomplish swimming in Lake Mead, and as a breast cancer survivor, to do it during Breast Cancer Awareness Month, all while raising crucial funds for cancer research with Swim Across America.”
Sarah was accompanied by her support boat that included her husband Ryan Willis, who served as pilot, their friend Craig Lenning, who was crew chief, and her friend Celeste Jacroux, who was her official time-keeper.
Sarah adds the Lake Mead swim to a long list of record-breaking feats.
Sarah Thomas is the first person to complete a four-way crossing of the English Channel in 54 hours and 10 minutes in 2019. She did so one year after completing treatments for breast cancer!
She holds the world record for the longest continuous (unassisted, non-wetsuit) swim done in current-neutral conditions. That record-breaking swim covered 104.6 miles over 67 hours in Lake Champlain (USA) in August of 2017.
She is the first person to complete a two-way crossing of the North Channel in 21 hours and 46 minutes in 2022. The North Channel is the body of water bounded by Northern Ireland (to the west), Scotland (to the east), Isle of Man (to the south), and the Atlantic Ocean (to the north).
She is the first person to complete a two-way swim of Lake Tahoe (lengthwise) in 2013. The swim is 42 miles and Sarah completed it in 22 hours and 30 minutes.
Though Sarah holds many records in open water swimming, in her words, she doesn’t swim to “be the first.” She swims large bodies of water because she loves seeing the beauty in each corner of the world.
“After my first visit to the Hoover Dam in February 2021, I knew I had to swim across Lake Mead,” said Sarah. “Water levels in the lake are in danger of dropping so low that a swim may not always be possible across this beautiful and important body of water.”
Sarah’s swim across Lake Mead started in South Cove, where her favorite river, The Colorado, enters the lake. She then followed the lake 47.5 miles until she ran out of water at the Hoover Dam.
Sarah hopes to raise money for Swim Across America through her monumental swims.
“I was diagnosed with stage two breast cancer in 2017 at the age of 35,” said Sarah. “It was a terrifying time and we didn’t know how much my treatments would impact my ability to swim in the future. Being able to partner with Swim Across America combines two of my passions: open water swimming and doing everything I can to fight cancer so that others won’t have to go through what I went through.”
Sarah has supported Swim Across America since 2018, when the inaugural Swim Across America – Denver swim was held in her home community. As a breast cancer survivor, she hopes to raise money for cancer research and bring hope and new treatment options to others.
“Cancer treatments tested me in a way I never thought possible,” noted Sarah. ”Despite undergoing chemotherapy, surgery, and radiation therapy, I never gave up on my dream of doing a swim that most people thought was impossible.”
A year after completing treatments, she did the impossible – becoming the first person to complete a four-way crossing of the English Channel.
Swim Across America was founded in 1987 with its first open water event in Long Island Sound. Since that time, the nonprofit organization has raised more than $100 million to fight cancer. In its 36 years of “making waves to fight cancer,” more than 100,000 swimmers and 150 Olympians have swum the circumference of the earth three times, uniting a movement to fight cancer that has created a groundswell of support spanning all generations. Today, more than 24 communities hold open water swims and charity pool swims each year, from Nantucket to under the Golden Gate Bridge, which support innovative cancer research, detection and patient programs.
Swim Across America’s funding of clinical trials for patients helped contribute to four FDA approved life-saving immunotherapy cancer treatments: Yervoy, Opdivo, Tecentriq and Keytruda. In June of last year, a clinical trial at Memorial Sloan Kettering was published in The New England Journal of Medicine that showed a 100 percent success rate in treating patients in a phase 2 clinical trial for advanced rectal cancer with dostarlimab, an immunotherapy treatment produced by GlaxoSmithKline. The clinical trial at Memorial Sloan Kettering was funded by early-stage grant funding from Swim Across America. More than 60 scientific grants are funded each year and there are now ten dedicated Swim Across America Labs at major institutions including: Children’s Healthcare of Atlanta, John Hopkins Medicine Baltimore, Rush University Medical Center Chicago, Baylor Scott & White Charles A. Sammons Cancer Center in Dallas, Memorial Sloan Kettering Cancer Center New York, Infusion Center at Nantucket Cottage Hospital, UCSF Benioff Children’s Hospital Oakland and San Francisco, the Seattle Cancer Care Alliance, The Swim Across America Pediatric Research Lab at Columbia University Medical Center New York, and at Meyer Cancer Center at Weill Cornell Medicine.
Swim Across America, Inc. (SAA) is dedicated to raising money and awareness for cancer research, prevention and treatment through swimming-related events. With the help of hundreds of volunteers nationwide and past and current Olympians, Swim Across America is helping find a cure for cancer through athleticism, community outreach and direct service. To learn more visitswimacrossamerica.org or follow on Facebook @SwimAcrossAmerica or on Instagram or Twitter @SAASwim.
New Programs Offer Fun, Fresh, and Exciting Ways for College Students to Make a Bigger Impact With Swim Across America
College Swimming Coaches Association of America, Inc. and Vasa are proud partners of College Cup Competition
CHARLOTTE, N.C., September 26, 2023 – Swim Across America (SAA) is pleased to announce two new programs aimed at college students and college swim teams who want to make a bigger impact in their community through leadership, fundraising, and friendly competition. The Swim Across America College Cup features 30+ collegiate, club and alumni teams and more than 1,000 participants all united to make waves in the fight against cancer through swimming. The second program is the SAA College Ambassadorprogram where 21 college swimmers and ambassadors have been selected to represent Swim Across America throughout the school year to help raise awareness on the importance of making waves to fight cancer. Both programs are supported through partnerships with College Swimming Coaches Association of America (CSCAA) and Vasa, the fitness training company for swimmers.
Swim Across America College Cup
Through December 1, 2023, college or college-affiliated swim teams will compete in the Swim Across America College Cup, a fundraising competition among collegiate teams in the U.S. Teams can participate by registering for one of Swim Across America’s open water charity swims, joining or starting a pool swim, or participating virtually through the SAA My Way program. Participants must be affiliated with a U.S-based college or university to be eligible to compete in the College Cup. Teams may consist of current college students, alumni or a mix of both, and can be as small as one person.
To date, more than 30 teams consisting of 1,000 participants are currently enrolled in the College Cup’s inaugural year. As the college swim season peaks, Swim Across America expects those numbers to increase and encourages teams, clubs and alumni groups who want to join to do so at swimacrossamerica.org/collegecup.
Members of the Emory University Swim and Dive team at the 2023 SAA-Atlanta event.
Members of the Providence College swim and dive teams at the 2023 SAA-Rhode Island event.
“One of the exciting aspects of the Swim Across America College Cup program is that it offers a new way for alumni to stay engaged with their college swim teams,” noted John O’Neill, head coach of the Providence College men’s and women’s swimming and diving programs and a long-time participant in Swim Across America open water swims. “It allows them to lead the next generation of athletes in the swimming world and instill a philanthropic mindset.”
Fundraising by the College Cup teams will support cancer research and clinical trials in the community in which teams register to swim. If teams are participating in a national pool swim, funds support the Swim Across America pediatric cancer research fund. Swim Across America offers 24 open water swims across the country and hundreds of pool swims each year.
The College Cup brings several exciting partnerships to Swim Across America, including the College Swimming Coaches Association of America (CSCAA) and Vasa, a fitness and rehabilitation company focused on peak performance for swimmers, surfers and triathletes.
As part of their partnership, CSCAA will recognize the top individual College Cup fundraiser at their annual awards ceremony.
“We are thrilled to rejuvenate the partnership between Swim Across America and the CSCAA,” said Samantha Barany, executive director of CSCAA. “The philanthropic efforts of Swim Across America are impressive and impact nearly everyone in some way with the fight against cancer. The open water events hosted by Swim Across America are an excellent opportunity for our college teams and athletes to engage in charitable endeavors within a familiar and loved environment – the water. We will continue to find more ways to collaborate and I believe this is just the beginning!”
Vasa will award a Vasa Trainer Pro model to two participating teams. One will be awarded to the top College Cup fundraising team and the second will be awarded to a randomly selected team participating in the College Cup. All teams have the opportunity to win through their participation.
Swim Across America College Ambassadors
Swim Across America is also excited to announce another new college initiative, the Swim Across America College Ambassadors program. College Ambassadors will be the face of Swim Across America at their college or university and lead efforts to raise awareness of Swim Across America’s mission to fund cancer research, clinical trials and patient programs by hosting charity swims. College Ambassadors are passionate about Swim Across America and help engage their peers, promote the Swim Across America mission and brand, and encourage their local communities’ involvement.
Earlier this year, Swim Across America invited college students to apply for the Swim Across America College Ambassadors program. Applicants were asked to share why they are passionate about Swim Across America, highlight any previous leadership experience, and outline their aspirations for participating in the program. More than 30 applications were reviewed by a Swim Across America selection committee and 21 college students were selected to be College Ambassadors for 2023. Students selected represent colleges across the country, including University of South Florida, Roger Williams University and Northeastern University.
Beyond their role as ambassadors, these students also serve as team captains for teams participating in the College Cup or any Swim Across America event. To learn about the Swim Across America College Ambassador program, visit swimacrossamerica.org/ambassadors.
Swim Across America was founded in 1987 with its first open water event in Long Island Sound. Since that time, the nonprofit organization has raised more than $100 million to fight cancer. In its 36 years of making waves to fight cancer, more than 100,000 swimmers and 150 Olympians have swum the circumference of the earth three times, uniting a movement to fight cancer that has created a groundswell of support spanning all generations. Today, more than 24 communities hold open water swims and hundreds of charity pool swims each year, from Nantucket to under the Golden Gate Bridge, which support innovative cancer research, detection and patient programs.
Swim Across America’s funding of clinical trials for patients helped contribute to four FDA approved life-saving immunotherapy cancer treatments: Yervoy, Opdivo, Tecentriq and Keytruda. In June of last year, a clinical trial at Memorial Sloan Kettering was published in The New England Journal of Medicine that showed a 100 percent success rate in treating patients in a phase 2 clinical trial for advanced rectal cancer with dostarlimab, an immunotherapy treatment produced by GlaxoSmithKline. The clinical trial at Memorial Sloan Kettering was funded by early-stage grant funding from Swim Across America. More than 60 scientific grants are funded each year and there are now ten dedicated Swim Across America Labs at major institutions including: Children’s Healthcare of Atlanta, John Hopkins Medicine Atlanta, Rush University Medical Center Chicago, Baylor Scott & White Charles A. Sammons Cancer Center in Dallas, Memorial Sloan Kettering Cancer Center New York, Infusion Center at Nantucket Cottage Hospital, UCSF Benioff Children’s Hospital Oakland and San Francisco, the Seattle Cancer Care Alliance, The Swim Across America Pediatric Research Lab at Columbia University Medical Center New York, and The Swim Across America Laboratory at Meyer Cancer Center at Weill Cornell Medicine.
About Swim Across America
Swim Across America, Inc. (SAA) is dedicated to raising money and awareness for cancer research, prevention and treatment through swimming-related events. With the help of hundreds of volunteers nationwide and past and current Olympians, Swim Across America is helping find a cure for cancer through athleticism, community outreach and direct service. To learn more visitswimacrossamerica.org or follow on Facebook @SwimAcrossAmerica or on Instagram or Twitter @SAASwim.
About CSCAA
Founded in 1922, the CSCAA is the nation’s first professional coaching association for intercollegiate athletics. The CSCAA boasts more than 2,000 member coaches and assistant coaches, recognizes All-American swimmers and divers, NCAA record-breakers and Scholar All-America athletes and teams, as well as outstanding coaches and contributors, and helps oversee the welfare of collegiate swimming and diving. Learn more about CSCAA at cscaa.org.
About Vasa
Vasa empowers swimmers, surfers and triathletes to become stronger, better, faster in sports, fitness and injury rehab. Vasa offers specific equipment such as swim ergometers, trainers, sport benches and other accessories to provide athletes with safe, effective training methods. Founded by Rob Sleamaker, an acclaimed exercise physiologist and author, who has worked with Olympians, biathletes and triathletes as well as some of the world’s most respected swim coaches to reinvent their training practices. Learn more about Vasa at vasatrainer.com.
Maya Merhige Swim Across America – San Francisco Age: 16
Maya Merhige is just 16 years old, and she has spent half her life participating in Swim Across America – San Francisco. In that time, she has raised over $76,000 for the swim’s beneficiary, UCSF Benioff Children’s Hospitals.
Maya Merhige
“I’ve loved swimming for a really long time,” noted Maya. “Swimming is something that I would do even if I weren’t raising funds. Being able to raise money for something that is extremely important to me and close to my heart by just continuing with something I love is the perfect situation.”
From a young age, Maya understood the importance of raising funds for cancer research. She first swam at Swim Across America – San Francisco when she was nine years old.
“I swim for each and every single person that has ever been touched by cancer. Whether it’s for a patient, a doctor, a family member, or a friend, I swim for them all,” said Maya.
“Cancer is one of the most devastating things to go through, and I swim to honor all of those who use all of their strength to fight this disease.
Using strength to fight through challenging situations is something Maya is familiar with. In addition to being a high school junior, a top fundraiser for Swim Across America, and a Taylor Swift fan, Maya is an accomplished marathon swimmer with several record-breaking and high-profile channel swims completed to make up a long list of achievements.
This summer, she completed her eighth major marathon swim, the 20 Bridges Swim around Manhattan. She was 15 at the time, becoming only the third 15-year-old to complete the swim, and swam the 28.5-mile course in eight hours and 43 minutes under the bright lights of New York City.
“I really like the challenge of it. I got to see all of the Manhattan skyline from the water at night, which is something I think not a lot of people can say. It was beautiful!”
Maya and her safety crew after the 20 Bridges Swim around Manhattan
Last January, Maya became the youngest swimmer in the world to successfully swim the grueling Kaiwi Molokai Channel, between the Hawaiian Islands of Molokai and Oahu, which she completed in 27 hours and 33 minutes. She also holds a record for the longest duration, thanks to an incredibly strong rip current.
She is the youngest woman to swim the 21-mile length, 12-mile width, and 10.8-mile Vikingsholm courses of Lake Tahoe, earning her the Tahoe Triple Crown. Read more about Maya, her marathon swims, and progress on fundraising efforts at swimacrossamerica.org/maya.
Maya plans on completing the Ocean’s Seven, which is a series of seven open water channel swims throughout the world. So far, she has completed two, and her English Channel swim is scheduled for July 2024.
Susan Helmrich, captain of Team Susan Survives and three-time cancer survivor, and Maya
Until then, she’s excited about the Swim Across America – San Francisco open water swim on September 30. She will swim with her team, Team Susan Survives, which has raised over $1 million throughout 17 years of support.
“This year marks the eighth year I’ve been swimming and raising money for Swim Across America – San Francisco,” said Maya. “I originally started swimming to support my dear friend Susan Helmrich, with Team Susan Survives. Susan is an amazing three-time cancer survivor!”
If you are moved to support Maya, you can donate here.
Swim Across America has raised $100 million since its inception in 1987 to support cancer research and clinical trials across the U.S. Please contact Jeni Howard at jhoward@jhowardpr.com for media inquiries.
Read or watch local stories featuring the Swim Across America-Chicago community to learn about their impact. Learn more about the event and beneficiary, Rush University Cancer Center at swimacrossamerica.org/chicago.
Read or watch local stories featuring the Swim Across America-Boston community to learn about their impact. Learn more about the event and beneficiaries, MassGeneral Cancer Center and Dana-Farber Cancer Institute at swimacrossamerica.org/boston.
Read or watch local stories featuring the Swim Across America-Nassau/Suffolk community to learn about their impact. Learn more about the event and beneficiaries, Memorial Sloan Kettering Cancer Center, Cold Spring Harbor Laboratory, the Feinstein Institute of Northwell Health, MD Anderson Children’s Cancer Hospital, SHARE Cancer Support, and Weill Cornell Medicine at swimacrossamerica.org/ns.
Read or watch local stories featuring the Swim Across America-Long Island Sound community to learn about their impact. Learn more about the event and beneficiaries, Memorial Sloan Kettering Cancer Center, Columbia University Medical Center, Cancer Support Team, and Weill Cornell Medicine, at swimacrossamerica.org/longisland.
Swim Across America 