5th Annual Swim Across America – Florida Keys Open Water Swim

Swim Across America – Florida Keys event directors, Glenn and Susan Latham, at the 2025 event.

For co-event director Glenn Latham, a cancer survivor himself, and his wife and co-event director Susan, holding the Swim Across America event in the Florida Keys is especially poignant to them. “We’ve known so many family members and friends whose lives have been touched by cancer,” noted Glenn. “By swimming, we can make a difference and hopefully play a part in helping fund better and more effective treatments.” The 5th annual Swim Across America – Florida Keys event will be held Saturday, April 18, on the beautiful key of Islamorada.

Latham was diagnosed with prostate cancer at age 53 in 2008. Although the diagnosis came in his early 50s, cancer had already touched his family deeply. Both of his parents and two of his three siblings battled cancer. His father also had prostate cancer, and his mother passed away at the young age of 48 from breast cancer, a disease that also affected two of his sisters — one who passed from the disease and one who, like Glenn, is a survivor. Today, after undergoing four years of treatment, Glenn is celebrating 18 years of being cancer-free.  

“As a cancer survivor, I was involved in several cancer causes prior to moving to The Keys. My love of swimming led to the chance meeting with a local swimmer and long time Swim Across America supporter, Bob Coakley, who shared the mission of Swim Across America. My wife Susan and I were immediately interested, and together we decided to organize a Swim Across America open water swim in the Florida Keys. I believe we need to expand cancer research – and the funding that Swim Across America and our swim generates is of huge value. It is particularly gratifying to meet and work with key members of the local medical research institution, Swim Across America staff, swim Olympians and local community supporters. I encourage everyone of all ages to please come out and join us on April 18th! It’s fun for everyone!”

Some of the top fundraising teams, like Team Baker, formed by siblings Chip and Mary Baker, are swimming in memory of loved ones lost to cancer, like Chip and Mary’s Mom. Team “The Importers” was formed by childhood best friends Casey and Bree, who were united by both having parents who underwent a cancer battle and are today survivors, or currently battling. “This year both our families got news we never expected to hear, but despite the road bumps in our paths, Miami Cancer Institute   has been there to help with treatment, support, and give us Hope in the darkest times. This is why we want to support them by participating with Swim Across America – Florida Keys,” noted Breeanna Prince, team captain. There are also the young teammates who have formed the Florida Keys Swim Club Team. “No one fights cancer alone,” noted Stella Hodder, team captain. “Our team joined Swim Across America because we believe in their mission and want to help give more families hope.”   Even Bob Coakley’s dog, Rona, swims in the event and is a top fundraiser!

The beautiful backdrop for the SAA – Florida Keys open water swim, at Founders Park in Islamorada.

“Our Swim Across America – Florida Keys open water swim is one of the most beautiful swims in the world,” noted Susan Latham, co-event director. “Sometimes we get lucky and a few dolphins decide to join us and swim alongside us. The sun is usually always shining, and the beauty of the beach, along with the passion of the swimmers, helps make the day unforgettable and inspiring. The gathering of so many families and so many individuals is incredible — whether they are currently battling it out, are survivors or have lost someone. To hear the stories and to learn about those whom cancer has touched and to experience that the outpouring of support is just amazing. The feeling of wanting to make a change and to do something for those who have experienced cancer is huge.”

The 5th annual Swim Across America – Florida Keys open water swim will take place on Saturday, April 18, 2026, at Founders Park, 87000 Overseas Highway, on the Florida key of Islamorada. The swim raises funds for critical cancer research and supports its local beneficiary Miami Cancer Institute. Since its first Florida Keys swim in 2022, Swim Across America – Florida Keys has raised more than $450,000 to fight cancer. This event proudly welcomes swimmers, volunteers (land and water), spectators, supporters and Olympians from near and far for this inspiring community swim. Swim lengths are ½-mile, 1-mile or 2-miles. There is also a fun Kids’ Splash and Mermaid Swim! Those interested in swimming, volunteering or donating can learn more at swimacrossamerica.org/floridakeys or follow on Facebook or Instagram @saafloridakeys or email glenn@swimacrossamerica.org.

Nationally, Swim Across America has raised more than $150 million for cancer research since its founding in 1987 and has helped fund clinical trials that contributed to the FDA-approved cancer immunotherapy medications Keytruda, Opdivo, Yervoy and Tecentriq. In the past year, Swim Across America funded a breakthrough clinical trial at Memorial Sloan Kettering that showed that immunotherapy alone could successfully treat certain types of cancer. The organization also recently awarded two first-of-its-kind gene editing innovation grants to the Alliance for Cancer Gene Therapy and Dana-Farber Cancer Institute, advancing novel CRISPR gene and base editing techniques used in targeted therapies, immunotherapies and cellular therapies. Swim Across America supports more than 60 cancer research projects annually, has eight named Swim Across America labs, and supports work at many of the nation’s leading cancer institutions.

Swim Across America – Charleston-Kiawah Holds Open Water Swim and Celebrates 10 Years of Making Waves to Fight Cancer on June 6, 2026

Hundreds of swimmers and volunteers are getting ready to dive in and make waves to fight cancer at the 10th annual Swim Across America – Charleston-Kiawah open water swim on Saturday, June 6, 2026, at Kiawah Island Golf Resort, Night Heron Park, on Kiawah Island in South Carolina. The event raises crucial funds for cancer research at the Hollings Cancer Center at the Medical University of South Carolina. Swimmers of all ages and skill levels are invited to take part in the annual Swim Across America – Charleston-Kiawah open water swim. Participants can swim a 1/2-mile or 1.5-mile open water swim, or participate in a same-day pool swim. For those not able to be there in-person, a SAA My Way virtual option is available. For registration and volunteer opportunities (volunteer on the land or water), or to support the swim with a tax-deductible donation, visit swimacrossamerica.org/charleston.

The SAA-Charleston-Kiawah community after the 2025 open water swim.

Established in 2017, Swim Across America – Charleston-Kiawah has raised more than $600,000 for its beneficiary, Hollings Cancer Center at the Medical University of South Carolina. Each year, the event proudly hosts more than 150 swimmers, volunteers, spectators and supporters, as well as Olympians from near and far, for this inspiring community swim.

“The Swim Across America – Charleston-Kiawah open water swim is one of the most inspiring events you will ever attend,” said Jana Chanthabane, event director of the Swim Across America – Charleston-Kiawah open water swim. “The gathering of so many families and individuals who are honoring those who have been touched by cancer, whether they are survivors, currently battling, or have lost someone, is truly incredible. The feeling of wanting to make a change and to do something for those who have experienced cancer is huge.”

Chanthabane knows firsthand the impact of raising funds for cancer research. She is a breast cancer survivor who has been cancer-free for 13 years. She was diagnosed in 2013 at the young age of 35 while raising three young children. Her personal journey is one of the reasons she has remained deeply committed to Swim Across America and its mission.

To support Jana, her family is swimming and volunteering with Team Chanthabanes Cheating Cancer. Jana’s daughter Ella Chanthabane notes that 2026 represents a powerful milestone.

“2026 marks Swim Across America – Charleston-Kiawah’s 10-year anniversary, and for me and my mom, that means 10 years of commitment to the mission,” said Ella Chanthabane. “Commitment to fighting cancer, making waves, and honoring those we’ve lost, as well as survivors like my mom, is really incredible. We got involved because, like everyone, we had been touched by cancer. We stayed because we believe in the Swim Across America mission and the work being done to support MUSC Hollings Cancer Center, where my mom was treated for breast cancer.”

Jana and Ella Chanthabane, pictured at the 2025 SAA-Motor City Mile open water swim.

Among this year’s participants is John Rhodes with Team Axes Endurance Club, who participates in memory of his father and in honor of many others affected by cancer. “I am passionate about Swim Across America and dedicate my time in memory of my father, John Rhodes, who was diagnosed with skin, prostate and thyroid cancer,” said John Rhodes. “In 2001, I began getting skin cancer screenings due to my father’s extensive skin cancer diagnosis and was found to have a basal cell carcinoma, which was successfully removed. Many other friends and family have been diagnosed with cancer, and Swim Across America’s goal of beating cancer through advancements in treatments has already resulted in the saving of many lives around the world. Without Swim Across America’s early-stage funding, researchers are not able to conduct trials that can lead to breakthroughs that save lives.”

Another returning swimmer is Ellen Sullivan with the team Pawleys Island Freestylers, who is taking part in her fourth Swim Across America event. “My journey with Swim Across America began four years ago when my high school swim coach and Olympic swimmer, Craig Beardsley, invited me to support the Kiawah event,” said Ellen Sullivan. “Since then, I have lost both my beloved mother and father to cancer. A close friend has bravely battled and triumphed over her own diagnosis, and my dear colleague continues to fight courageously against recurring cancer. These personal experiences have given me even more reason to swim. I swim to make a difference.”

Sullivan’s teammate Stefanie Whitmire, also with Team Pawleys Island Freestylers, is swimming as both a survivor and an advocate for others facing the disease. “I joined Swim Across America for so many reasons,” said Stefanie Whitmire. “I have many friends who have fought cancer, and this year, I am also swimming for myself. I have never been as scared as when I found out I had cancer — especially when it was a rare cancer. The news was unexpected and came right before Christmas. My surgeons and doctors were amazing. They saw me through two major surgeries, six months of chemotherapy and continued monitoring. I learned so much about my inner strength, my faith and my determination. I want to give back and support the research that will fight cancer. I want others to see there is hope and life in the darkness.”

Irene Row with Team West Ashley Whales is also swimming for a loved one. Her husband, Michael, was diagnosed with neuroendocrine cancer in 2017 and continues to fight the disease. “My husband, Michael, was diagnosed with neuroendocrine cancer in 2017, and he has been fighting this disease ever since,” said Row. “We both have family members and friends with other forms of cancer, and some of them have passed away. Michael found out about Swim Across America in 2018 and we both love that it raises money for a worthy cause — funding much-needed cancer research.”

Another standout returning team is Team Baucom, led by Barry Baucom of Kiawah, along with his wife Louise and son Ryan, who happens to be vice president of marketing for Swim Across America. The family has raised more than $60,000 over the past ten years to support cancer research and clinical trials at Hollings Cancer Center.

Team Baucom at the 2025 SAA-Charleston-Kiawah open water swim.

The funds raised by Swim Across America – Charleston-Kiawah support cancer research and clinical trials at the MUSC Hollings Cancer Center, with funds currently supporting both the Ferreira Lab, dedicated to designing and developing engineered immune cell therapies for autoimmune disease, cancer and aging, as well as a pediatric brain cancer grant.

Nationally, Swim Across America has raised more than $150 million for cancer research since its founding in 1987 and has helped fund clinical trials that contributed to the FDA-approved cancer immunotherapy medications Keytruda, Opdivo, Yervoy and Tecentriq. In the past year, Swim Across America funded a breakthrough clinical trial at Memorial Sloan Kettering that showed that immunotherapy alone could successfully treat certain types of cancer. The organization also recently awarded two first-of-its-kind gene editing innovation grants to the Alliance for Cancer Gene Therapy and Dana-Farber Cancer Institute, advancing novel CRISPR gene and base editing techniques used in targeted therapies, immunotherapies and cellular therapies. Swim Across America supports more than 60 cancer research projects annually, has eight named Swim Across America labs, and supports work at many of the nation’s leading cancer institutions.For those interested in swimming, volunteering or donating at the 10th annual Swim Across America – Charleston-Kiawah open water swim on June 6, 2026, visit swimacrossamerica.org/charleston, or follow on Instagram and Facebook @saacharlestonkiawah.

Thank You – Message of Appreciation

The current image has no alternative text. The file name is: screenshot-2025-12-29-at-11.09.56-am.png

Thirty-eight years ago, college lacrosse players and retired Olympians attempted the first-ever relay swim across Long Island Sound. The swim was challenging. The intent was simple. Raise awareness and donations for cancer research and detection, and to innovate treatment and improve the quality of life.

​We’ve grown from a single relay to more than 60,000 volunteers and donors this year, a record number of donors for SAA. In the first year, we raised $5,000. This year, we raised $12.4M, another record for SAA.

​Just like our grant fellows are innovating new cancer treatments and improving the quality of life, Swim Across America is innovating.

We’ve made it easier and added more ways for donors to give. We’ve integrated employer match giving. Impact reports are featured on each community’s swim page. We introduced Dash, our dolphin mascot, to bring energy and smiles to the swims and hospital visits.

​We are integrating seamless donor-advised fund giving. We are simplifying the self-registration process. Teams are recognized on our Champions Wall. Chapters are establishing “Junior Advisory Boards” to provide high school students with volunteer and leadership development opportunities. More of your stories are being shared.

Phoenix is a new SAA community, and more colleges are hosting SAA charity swims, expanding our coast-to-coast reach. New WaveMaker recognition is coming. And more.

​Our investments honor the spirit of the 1987 relay swim. Raise awareness and donations for cancer research and detection, and to innovate treatment and improve the quality of life.

I’m often asked how someone can get involved with Swim Across America. A few ideas come to mind. Volunteer with your local SAA chapter, invite your friends to join the cause, and share stories with donors about our impact.

​Our community, the grants, and the stories wouldn’t be possible without you.

​Thank you for Making Waves to Fight Cancer,
Rob Butcher
Swim Across America |CEO

Swim with a Purpose: CLASH Endurance Announces New Charity Swim Events with Swim Across America

1-Mile Swim and 100M Dolphin Dash Take Place December 7 at Daytona International Speedway

CLASH Endurance® and Swim Across America are thrilled to announce a new charity swim in Lake Lloyd, located in the infield of the iconic Daytona International Speedway® on Sunday, Dec. 7, 2025. Participants of all ages will have the opportunity to swim alongside notable Olympians in an inspirational one-mile swim or a 100-meter Dolphin Dash with fundraising for critical cancer research as their top priority. Funds raised will support Swim Across America’s breakthrough pediatric cancer grants with its beneficiaries and CLASH Endurance’s philanthropic partner The NASCAR Foundation.

Swim Across America, founded in 1987, hosts 24 annual open-water swims from Nantucket to under the Golden Gate Bridge, and hundreds and pool swims each year that fund cancer research and patient programs, raising more than $100M to date. Swim Across America has funded transformative trials that led to the FDA-approved immunotherapy cancer medications Keytruda, Opdivo, Yervoy and Tecentriq. The organization has also supported Memorial Sloan Kettering’s landmark trials including the recent Phase II clinical trial published in The New England Journal of Medicine showing an 80% success rate treating MMRd cancers with immunotherapy alone. Swim Across America also recently awarded the first-of-their-kind gene editing innovation grants to Alliance for Cancer Gene Therapy and Dana-Farber Cancer Institute to advance safer, more effective targeted treatments.

“Swim Across America, CLASH Endurance and The NASCAR Foundation joining together makes so much sense as The NASCAR Foundation helps so many kids who are battling cancer,” commented Rob Butcher, CEO of Swim Across America. “To have a Swim Across America charity event in Daytona on the CLASH Endurance Family Weekend means we will make even bigger waves together in the fight against cancer.”

The NASCAR Foundation is a leading charity that works to improve the lives of children who need it most in NASCAR racing communities through the Speediatrics Children’s Fund and the Betty Jane France Humanitarian Award. Serving as a designated 4-Star Charity by Charity Navigator for its strong financial health and ongoing accountability and transparency, it has contributed more than $50 Million to impact the lives of more than 1.7 million children nationwide since 2006.

“We are excited to be a part of the new Swim Across America swim during the CLASH Endurance weekend at Daytona International Speedway. We truly appreciate the many years of support from our friends at CLASH, and it is a privilege to team up again to help improve the health and well-being of kids across the country and in our race communities,” said Nichole Krieger, vice president and executive director of The NASCAR Foundation.

On December 7, when hundreds of swimmers and volunteers dive into Lake Lloyd, one-mile swimmers will be required to raise at least $400 by event day; swimmers under 18 will raise a minimum of $200; Dolphin Dash participants can register for $50 and have no fundraising minimum. To register as a swimmer or a volunteer, visit swimacrossamerica.org/daytona.

CLASH Endurance CEO Bill Christy says, “We are proud to collaborate with Swim Across America which continues to make a lasting impact in the cancer community. This is a cause that has touched all our lives, and we are honored to further support the fight at one of our flagship event weekends.”

Each December when much of the country battles snow, more than 3,000 participants ranging in age from four to 80+ will take on the speedway through a variety of events including a 5K, kids’ triathlon, duathlon, aquabike, triathlons, Test Track and Redline Relay. CLASH Endurance strives to provide a festival-style weekend, which in addition to free activities for spectators and athletes alike, include a wellness expo, food trucks, beer/wine garden and much more. The weekend kicks off with a festive “Jingle Jog 5K” on Friday evening with a start and finish at ONEDaytona. Participants, including those in jogging strollers, will experience Florida’s “Magic of Lights” holiday display taking them under the iconic grandstands of the speedway. The Swim Across America 1-mile swim and Dolphin Dash will help cap-off the weekend on Sunday, December 7.

“We have swum in some incredible venues and Daytona International Speedway is certainly one of the most iconic,” noted Olympic swimmer and Swim Across America Ambassador Rowdy Gaines. “To have a Swim Across America charity swim in Daytona is going to be extra special – I will definitely be there!”

CLASH Endurance® is an innovative endurance event company led by athletes with a passion to provide exceptional race experiences at iconic speedways across the U.S. CLASH embraces inclusion and welcomes athletes of all ages and abilities, from elite professionals to first-time participants. The popular CLASH Endurance DAYTONA event is held at the Daytona International Speedway®, home of ‘The Great American Race”- the Daytona 500, and has been featured on NBC and Fox Sports 1/2. Each February, the Daytona Beach Half Marathon & 5K takes athletes on a scenic tour of Daytona and its numerous landmarks and attractions. In addition, CLASH Endurance Miami in March continues to draw a decorated pro field, collegiate athletes from dozens of prestigious universities and weekend warriors for a challenging course at the historic Homestead-Miami Speedway®. Follow The NASCAR Foundation on Facebook at www.Facebook.com/NASCARFoundation or on X at @NASCAR_FDN. For more information visit clashendurance.com.

Swim Across America hosts open water and pool swims in numerous communities nationwide, from Nantucket to under San Francisco’s Golden Gate Bridge. More than 150 Olympians swim with the organization, including Michael Phelps, Kate Douglass, and Missy Franklin. The organization supports more than 60 cancer research projects annually and has ten named Swim Across America Labs at major institutions nationwide. To learn more, visit swimacrossamerica.org or follow on social media @SwimAcrossAmerica on Facebook and @SAASwim on Instagram.

11-Year-Old Shep Jennings Makes Big Waves to Fight Cancer

Shep Jennings is proving that even the youngest swimmers can Make Waves to Fight Cancer! The Darien, Connecticut resident will swim at the 2025 Swim Across America – Fairfield County open water swim on June 21.

Shep Jennings

Shep, who swims year-round with the Darien YMCA Piranhas and in summer with Shorehaven Golf Club, first dove into the charity swim event last year when his swim buddy Jedd Gallagher asked Shep to join the Blue Wave Swim Team, which was participating in the annual Swim Across America – Fairfield County open water swim. The Blue Wave Swim Team was coached by longtime Swim Across America supporter Marj Trifone.

Last summer was the start of a fulfilling experience for Shep, who raised more than $2,000 for the nonprofit in 2024. Seeing his name on the leaderboard last year was inspiring to know he was making a difference.

“I love seeing my name climb the leaderboard, because every dollar means scientists get closer to cures,” said Shep.

The Jennings family

Inspired by watching his parents raise money for ALS research after his grandmother was impacted by the disease, Shep already had the know-how of fundraising down. For Swim Across America, he began emailing friends and family and even going door-to-door in his neighborhood to collect pledges.

Shep, who will turn 12 in September and enter Middlesex Middle School in the fall, acknowledges his favorite summer sports are all about water: swimming, water polo and water-skiing on summer weekends, in the winter, he swaps liquid water for frozen water with snow-skiing. At home he shares the spotlight with his nine-year-old sister, Emmaline, and the family’s golden retriever, Rosie. With just a few weeks left until the big SAA – Fairfield County open water swim, Shep isn’t easing up on his fundraising pace.

Shep, far right, and a few of his teammates

“I’m still reaching out,” he said. “I want my total and the funds for cancer-fighting research to keep growing.” To date, Shep is the number one individual fundraiser already raising $6,080.

If you’re inspired to support Shep, give here.

Sarah Wiseman Makes Waves for SAA-Nashville and the Cancer Care Team Who Helped Her to Achieve Remission

When Sarah Wiseman was diagnosed with breast cancer in June 2022, it came as a complete shock. Though her mother had been diagnosed with the same cancer in her 60s, Sarah’s genetic marker testing had come back negative. It was a routine mammogram that led to her breast cancer diagnosis.

“I had a routine mammogram that was concerning, which led to further diagnostic testing—an ultrasound and a biopsy,” Sarah explained.

“I had a seed inserted via biopsy, then underwent a partial mastectomy/lumpectomy and lymph node removal during surgery. One lymph node tested positive for metastasis. After healing from surgery, I received radiation treatment on my lymph nodes and left breast — 20 treatments in total. I’m grateful to have had access to a tumor test that evaluated the effectiveness of chemotherapy on my specific tumor. The results came back below the threshold for needing chemo!”

Sarah Wiseman, a member of the SAA-Nashville committee, was declared in remission from breast cancer in 2023.

This year, Sarah celebrates her remission and looks forward to swimming in the 4th Annual Swim Across America – Nashville. Funds raised from the event support Vanderbilt-Ingram Cancer Center (VICC), where Sarah received treatment.

Sarah swam as a child but really fell into the sport watching her children swim on club teams and in college. Once she got the all-clear from her doctors, Sarah knew exactly how to get her strength back while doing something she loved.

“After I healed from my surgeries, I couldn’t wait to swim. I joined the local Masters team, and thanks to my friend Chris McPherson, I was introduced to Swim Across America,” said Sarah.

Chris McPherson, along with Alyssa Corb and Laurin Bobo, is a co-event director for SAA-Nashville.

“This community event is a wonderful way for me to give back to the doctors, nurses, and caregivers who took such great care of me during treatment,” Sarah said.

Swim Across America’s guiding principle is that money raised locally stays local — something that resonated deeply with Sarah. She takes great pride in supporting an organization that directly benefits her community, especially given her firsthand experience with how much cancer treatment has evolved.

Members of the SAA-Nashville committee and researchers from Vanderbilt-Ingram Cancer Center present the fundraising total at the 2024 SAA-Nashville community pool swim.

“In the past, having a positive lymph node would have meant automatic chemotherapy. Today, I am closely monitored by my medical oncologist and surgical oncologist at Vanderbilt Breast Center. And I’m proud to be raising funds for others in our community—people who will be treated at VICC, just like I was,” said Sarah. “I am a beneficiary of the incredible advances in cancer treatment. My mother didn’t have access to these options during her fight. She really struggled, and I believe newer-generation treatments made my journey much easier.”

Now in remission, Sarah is grateful that Swim Across America allows her to support two of her greatest passions: swimming and the cancer care team at VICC.

“I just feel incredibly blessed to have received the life-saving treatment I did,” Sarah shared. “Swimming has had the best impact on my health, and since my cancer diagnosis, I’ve embraced a much healthier lifestyle. I love that SAA allows me to give back through two of my favorite things: swimming and Vanderbilt-Ingram Cancer Center.”

If you’re inspired to support Sarah and team Wisemans Wack Cancer, give here.

Swim Across America – Seattle Shares 2024 Impact Report and Progress Updates

For 15 years, Swim Across America has fueled innovative early-stage research at Fred Hutch Cancer Center and UW Medicine and helped launch the careers of dozens of young scientists. We’re proud to share details about the six most recent projects made possible through funds raised in 2022 and 2023 by Swim Across America – Seattle and the dedicated swimmers who participated. From improving patients’ quality of life to overcoming tumors’ resistance to immunotherapy, these innovative projects have the potential to dramatically enhance cancer treatment.

Inspired to Make Waves to Fight Cancer this year? Swim, volunteer or donate to SAA-Seattle at swimacrossamerica.org/seattle.

Kate Markey, MBBS, PhD, FRACP | Stem cell transplantation

Assistant Professor, Fred Hutch and UW Medicine

Project: Restoring the gut microbiome after blood stem cell transplant

Dr. Kate Markey

Background: Fred Hutch researchers have shown that while blood stem cell transplantation continues to be the most effective treatment for multiple myeloma, it can also severely damage patients’ gut microbiome, leading to strong gastrointestinal side effects and poor outcomes. Dr. Markey, a medical oncologist who studies the gut microbiome and its role in recovery from transplant, developed a study to examine whether a five-week, plant based, whole-food diet can restore patients’ beneficial gut bacteria and improve immune function and outcomes.

2024 progress statement: Dr. Markey and her colleagues opened the trial in October, and by the end of the following month they had enrolled seven patients, or one-third of their goal. They are collecting stool and blood samples and plan to analyze all of them once the trial is complete. If all goes as expected this summer they intend to use the resulting data to apply for a federal research grant to support a much larger, randomized clinical trial.

Alexandre Hirayama, MD  |  Blood cancers

Assistant Professor, Fred Hutch and UW Medicine

Project: Understanding how large B-cell lymphoma evades CAR T-cell therapy

Dr. Alexandre Hirayama

Background: Less than half of patients who undergo CAR T-cell therapy for large B-cell lymphoma (LBCL) enjoy long-lasting remission. We’re not sure why, but the answer may lie in the tumor microenvironment. There’s still so much we don’t know about this collection of cells, stroma, and blood vessels that surround and support the tumor, including how it might suppress cancer therapies. Dr. Hirayama, who specializes in treating patients with B-cell malignancies, is studying the tumor microenvironment in minute detail to help identify and explain how patients’ tumors may mute CAR T cells’ effectiveness.

2024 progress statement: Dr. Hirayama has gathered the necessary tumor samples for these studies and refined the techniques and technologies that will allow him to study immune, stromal, and tumor cells in the tumor microenvironment. He expects to begin studying the samples in summer 2025.

Diane Tseng, MD, PhD  |  Lung cancer

Assistant Professor, Fred Hutch and UW Medicine

Project: Reducing inflammatory effects of immunotherapy in patients with lung cancer

Dr. Diane Tseng

Background: Many patients with lung cancer who are treated with checkpoint inhibitors experience a condition called checkpoint inhibitor pneumonitis (CIP). If left untreated, CIP can cause irreversible damage. Recent research shows that immune cells called napsin A–specific T cells may be involved in mediating CIP. Dr. Tseng, an oncologist who specializes in treating patients with lung cancer, is working with McGarry Houghton, MD — a Fred Hutch and UW Medicine professor and holder of the Satya and Rao Remala Family Endowed Chair — to study napsin A–specific T cells’ role in CIP and exploring strategies for muting it.

2024 progress statement: Dr. Tseng’s work has focused on 1) developing a method for detecting napsin A– specific T cells in donor blood; 2) developing a method for taking those cells and growing more of them in the lab; and 3) creating a test to determine whether a different T cell can eliminate them. This work will establish the foundations for understanding the function of napsin A–specific T cells and the role they might play in CIP.

Emily Liang, MD  |  Blood cancers

Hematology/oncology Fellow, Fred Hutch and UW Medicine

Project: Mitigating serious side effects of CAR T-cell therapies in patients with blood cancers

Dr. Emily Liang

Background: While CAR T-cell therapy has revolutionized treatment for patients with blood cancers like lymphoma and multiple myeloma, it also comes with a high risk of fever, fatigue, body aches, and even neurologic impairment. Though these conditions are reversible, they can be life-threatening and prevent older and frailer patients from receiving CAR T-cell therapy at all. Dr. Liang, who specializes in acute leukemias and CAR T-cell therapy, and her mentor, Jordan Gauthier, MD, MSC, a Fred Hutch and UW professor and former Swim Across America funding recipient, want to make these treatments accessible to a wider range of patients. So, the pair launched a first of-its-kind trial to study whether a drug typically prescribed for rheumatoid arthritis called anakinra can prevent these inflammatory responses.

2024 progress statement: After treating more than 30 patients in their clinical trial, Drs. Liang and Gauthier found that prophylactic administration of anakinra did not seem to be effective in preventing cytokine release syndrome, a side effect associated with a high level of inflammation in the blood. However, prophylactic anakinra did seem to reduce the severity and duration of neurologic side effects as well as the need for steroids. Importantly, Drs. Liang and Gauthier also found that anakinra may impair the treatment’s effectiveness against tumors. Now, the pair are planning to study how anakinra mitigates inflammation in the brain, whether there may be alternative prevention strategies, and how anakinra impacts CAR T-cell function.

Saurav Kumar, PhD  |  Colorectal cancer

Postdoctoral Fellow, Fred Hutch

Project: Exploring new uses for existing drugs to treat colorectal cancer

Dr. Saurav Kumar

Background: Colorectal cancer is one of several cancers driven by a process called gene fusion, in which two independent genes combine incorrectly and begin producing proteins that can lead to cancer. And though a range of drugs have been developed to target these fusions and stop the mechanism that promotes cancer growth, they’ve so far been ineffective against colorectal cancer. However, Dr. Kumar, who studies metastasis, recently discovered that patients with colon cancer who receive TRK inhibitors (TRKi) experience a drop in TRK fusion protein levels, suggesting that these inhibitors may be degrading the cancer-causing fusion proteins. He plans to study the interaction that causes this protein degradation with the goal of one day using TRKi to create more effective therapies for patients with this form of cancer.

2024 progress update: Dr. Kumar and his colleagues have developed three protein degraders, called PROTACs, based on an FDA-approved TRKi. Now they plan to begin testing them on colorectal cancer cells in the lab to better understand the mechanism that leads to TRK fusion protein degradation — which could one day inform the development of targeted therapies for patients with these cancers.

Yapeng Su, PhD  |  Pancreatic cancer

Postdoctoral Fellow, Fred Hutch

Project: Overcoming solid tumors’ resistance to immunotherapies

Dr. Yapeng Su

Background: Pancreatic cancer is notoriously difficult to treat. Though we’ve found a protein on tumor cells that would seemingly make for a good immunotherapy target, treatments that have been studied and validated in the lab fail in patients — likely due to unique characteristics of the tumor microenvironment. Using technology that allows us to see the interaction of cells within tumors and better understand how they influence one another, Dr. Su, who studies adoptive cellular immunotherapy, is examining the mechanisms that cause immunotherapies to fail and exploring techniques to overcome them.

2024 progress statement: After completing a detailed study of samples from tumors previously treated with adoptive T cell therapy, Dr. Su found that they contained several cell types that were both potentially immunosuppressive and arranged in distinct patterns throughout the tumor microenvironment. He also identified several subtypes of T cells (whose role is to attack cancer cells) that no longer functioned properly. In the coming months, Dr. Su plans to further analyze the T-cell subtypes and their placement within the tumor microenvironment to better understand why they stop working. What he finds could one day help us better engineer T cells to overcome those immunosuppressive forces.

Swim Across America Presents the ASCA 2025 World Clinic Scholarship

Swim Across America is proud to announce a partnership with the American Swimming Coaches Association (ASCA) to sponsor a scholarship for a deserving coach to attend the 2025 ASCA World Clinic in Reno, Nevada, September 2-5.

The Swim Across America Scholarship provides full registration for the ASCA World Clinic and covers accommodation at the Peppermill Reno hotel and up to $500 for travel.

The ASCA World Clinic, now in its 58th year, is the largest and most comprehensive annual gathering in the sport of swimming. The event features 50 speakers covering a wide range of topics, an expansive exhibition hall, coaching demonstration at an Endless Pool, and numerous socials and networking opportunities.

This initiative is part of SAA’s commitment to supporting ASCA advancing the sport of swimming and the professional growth of dedicated coaches across the nation.

Applicants must be ASCA members who have never attended a World Clinic. Interested candidates are encouraged to complete the online application by February 28, 2025. The scholarship recipient will be notified by March 31, 2025.

“We deeply appreciate Swim Across America for their generosity and dedication to supporting the coaching community,” said ASCA CEO Jennifer LaMont. “This scholarship underscores their acknowledgment of the critical role coaches play in developing athletes and teams. We can’t wait to welcome the scholarship recipient to Reno this September.”

For more information about the ASCA World Clinic and the Swim Across America scholarship, and to apply, go to www.ascaworldclinic.com.

About Swim Across America
Swim Across America is a nonprofit organization dedicated to raising funds for cancer research through swimming-related events. Since its inception in 1987, Swim Across America has raised over $100M to fund groundbreaking cancer research and clinical trials. Learn more at www.swimacrossamerica.org.

About ASCA
The American Swimming Coaches Association (ASCA) is the professional association for swim coaches dedicated to inspiring, supporting, and advocating for coaches in the US and worldwide. Through education, certification, and professional development, ASCA empowers coaches to lead swimmers toward excellence while advancing the sport of swimming. Learn more at www.swimmingcoach.org.

CSCAA Honors Swim Across America CEO, Rob Butcher, with Richard E. Steadman Award

Congratulations to Swim Across America President and CEO, Rob Butcher, for receiving the prestigious Richard Steadman Award from the College Swimming Coaches Association of America (CSCAA).

This recognition honors his exceptional leadership, dedication, and contributions to the swimming community and the fight against cancer with Swim Across America.

As the President and CEO of Swim Across America since 2016, Butcher has guided the organization through tremendous growth and success. Under his leadership, Swim Across America has continued to expand its reach, with events across the country raising millions of dollars annually to support cancer research and treatment. His passion for SAA’s mission is deeply personal: both his grandmother and stepmother were cancer survivors, and his mother, whom he calls his hero, lost her battle with appendix cancer in 2007.  

Before joining SAA, Butcher served as Executive Director for U.S. Masters Swimming (USMS) for seven years. During his tenure, he transformed USMS into a professionally managed organization, developing the creation of the Masters Coach Certification and Adult Learn-to-Swim programs. Under his leadership, membership grew by more than 50%, and revenue tripled to $3.6 million.  

A Georgia Southern University graduate and competitor in the 2000 U.S. Olympic Trials, Butcher has demonstrated a lifelong commitment to the sport of swimming.

His leadership at SAA has been instrumental in expanding its impact, with the organization raising over $100 million for cancer research since its inception in 1987.  

“Rob Butcher exemplifies the very spirit of the Steadman Award—leadership, integrity, and an unwavering commitment to serving others,” said Samantha Barany, Executive Director of the CSCAA. “Through the water, he fights cancer every day, and we are all better off for his dedication to making a difference. Rob has profoundly impacted the swimming community and every community where Swim Across America has a presence. His passion for people and his ability to spread happiness wherever he goes are truly inspiring.”

Rob Butcher resides in Charlotte, North Carolina, with his wife Allison and their twin boys. He remains an active advocate for cancer research and a unifying force within the swimming community. His receipt of the Richard Steadman Award highlights not only his professional achievements but also his heartfelt commitment to making a lasting impact in the fight against cancer. For more information about Swim Across America and its mission, visit swimacrossamerica.org.  

SWIM ACROSS AMERICA – CHICAGO CELEBRATES 30 YEARS OF MAKING WAVES TO FIGHT CANCER

In 1994, Swim Across America – Chicago debuted as a 6-mile relay swim in beautiful Lake Michigan and raised $15,000. Since then, the annual community event has grown to raise more than $5 million for their local beneficiaries.

On Saturday, August 3, hundreds of swimmers, volunteers, and supporters will gather at beautiful Lake Michigan to celebrate 30 years of Making Waves to Fight Cancer! Proceeds from the event support cancer research at Rush Medical Center. 

For some swimmers, like 14-year-old Alondra Beening, it will be their first time diving into the lake on a meaningful and inspiring day. For others, like Mary McCullagh and Mary Holloway, the day represents a three decade long commitment to the Swim Across America mission. 

“I swam at our first swim in 1994 and I’ve had the privilege of watching the community’s support grow over the years,” shared Mary McCullagh. 

Mary credits a community of “doers and givers” for the success and longevity of Swim Across America – Chicago. Her family first became involved not because they had a personal connection to the cause, but because they grew up with a servant leadership mindset.

Mary McCullagh, center, at the inaugural Swim Across America – Chicago event in 1994.

“I have 10 brothers and sisters and we were taught to recognize a need and do something to help. Whether it is time, talent, or effort, we can all do something good in this world,” said Mary M.

“Even when I didn’t live in Chicago, my band of siblings helped to keep our support going. This event has been successful for 30 years thanks to this community of leaders who all want to do good.”

Mary Halloway’s involvement began 29 years ago as a passerby supporting her brother, Russ. Russ was an endurance swimmer who swam at SAA-Chicago and became the resident “event day chef” preparing food and snacks for the swimmers on the morning of the event.

Mary Halloway joins Swim Across America – Chicago for the 12th year this year. She was introduced to the organization by her brother, Russ Haffner.

“I started riding my bike down the lakefront to see him swim, and I would scream ‘Go, Russ!’ every time his arm was raised as he swam,” Mary H. said. “I don’t know how, but somehow he heard me every time, and he’d give me a wave on each stroke.”

Unfortunately, Russ passed away a few months after a lymphoma diagnosis in 2011. The SAA-Chicago leadership team knew they wanted his memory to live on so they created a special award to recognize outstanding community members, named the Russ Haffner Award.

Mary’s connection to SAA-Chicago became more personal when she was diagnosed with ovarian cancer in 2010. She was treated at Rush with chemotherapy and a hysterectomy, and was given the all-clear in early 2011. Though she wasn’t a natural swimmer, Mary was determined to swim at SAA-Chicago and honor her brother’s memory. This year will be her 12th year participating in the event.

The 30th annual event will also recognize rookie participants – those who are swimming for the first time!

Alondra Beening has watched her dad, Mark Beening, swim at SAA-Chicago for the last 10 years and this year, at 14 years old, she will join him as a 1-mile swimmer. Alondra has been swimming her whole life and on a swim team since she was eight years old. She’s excited to join her dad and honor their loved ones through the community swim.  

“She’s always wanted to swim with me since she was younger, and we are so happy to finally have this opportunity – and it is my 10th year swimming so it’s really special” shared Mark. “Unfortunately, we have had friends and family members who have been diagnosed with cancer, some of which we have lost. We want to dedicate this swim to them.” 

Swim Across America – Chicago is led by co-event directors, Alyse Mauro Mason and Katie Marchetti. Both have watched not only the community support grow, but also the waves of impact the event has had on the local beneficiaries. 

“Our event has supported Rush since 2012 and we’re proud to have donated more than $2 million to the cancer center here in Chicago,” said Alyse.

Co-event director, Alyse Mauro Mason, right, presented the 2023 Russ Haffner Award to Cathi McNamara at the 2023 SAA-Chicago event.

“Swim Across America – Chicago grants early-stage research and helps doctors begin and continue research that may be on the brink of a breakthrough,” Alyse continued. “We often hear that our doctors have received additional grants or NIH funding thanks to the findings and outcomes they have gathered from a project we have funded.”

SAA-Chicago hosted their fourth annual golf outing in June 2024 at Cog Hill Golf and Country Club. The event also raises funds for Rush Medical Center and will celebrate its fifth year on June 16, 2025.

In fact, in 2022, the NIH honored Rush physician scientist Dr. Faraz Bishehsari with the Director’s Transformative Research Award, which includes funding for his innovative pancreatic cancer research. The award, one of the NIH’s most prestigious and exclusive, is given to “exceptionally creative” scientists proposing high-risk, high-impact research. Dr. Bishehsari’s research was also supported by our Swim Across America – Chicago charity swim.

Though the swim course has changed – and the number of participants has grown exponentially – one thing remains: Swim Across America – Chicago is a community dedicated to Making Waves to Fight Cancer year after year.

Register to swim or volunteer at the August 3 Swim Across America – Chicago open water swim, or donate at swimacrossamerica.org/chicago

Read more stories about Swim Across America – Chicago here.