Read or watch local stories featuring the Swim Across America – Fairfield County community to learn about their impact. Learn more about the event and beneficiary, Alliance for Cancer Gene Therapy, at swimacrossamerica.org/fc.
Swimming a one-mile open water swim is challenging, but swimming a one-mile open water swim with cancer is nothing short of remarkable. David Lemley is one of those remarkable people.
David, with his wife, Janie, swam at the 2024 SAA-Seattle open water swim, while fighting plasma cell leukemia.
David, 65, first participated in Swim Across America – Seattle in 2021 supporting his wife, Janie’s, team “InMemory”, named for the loved ones she lost to cancer. Over the years, their team has raised more than $8,000. It wasn’t until this year that David’s understanding of cancer became very personal.
“Last year, I really struggled to finish the swim,” said David. “The reason being, unbeknownst to us at the time, that I was fighting plasma cell leukemia, a very rare and aggressive form of blood cancer.”
This may seem like a rare occurrence, but often Swim Across America participants become fighters of their own cancer battles, giving their involvement a new meaning and a sense of urgency.
“Swim Across America is extremely important to help fund urgent and necessary research in order to help more people become cancer survivors. SAA gives hope to those, like myself, who are fighting the cancer battle right now,” shared David.
David’s stem cells were harvested at Fred Hutch Cancer Center, the beneficiary of the SAA-Seattle swim.
Swim Across America’s guiding principle is that money raised local stays in each community. In Seattle, all proceeds from community events support immunotherapy clinical trials and cancer research at Fred Hutch Cancer Center.
Participants that fundraise know that the funds they raise will support their community to help people they may know, or in David’s case, his own treatment. Despite being a fundraiser year after year, David never imagined he would become a direct recipient of the treatment himself and hundreds of other swimmers help support.
After receiving his diagnosis in November 2024, David was thrown into a new world of hospital visits and chemotherapy treatment. As he prepared for his double stem cell transplant at the VA Medical Center near his hometown, David had his first visit to Fred Hutch Cancer Center (FHCC).
“I was at the VA for 13 days and then headed to Fred Hutch for the incredible procedure of Apheresis, where they harvest 17 million of my stem cells. Janie and I wore our Swim Across America t-shirts to commemorate this very special day,” said David.
David and Janie proudly wore their Swim Across America shirts during David’s stay at FHCC.
“On Monday, May 5th, I celebrated my new ‘birthday’ with the first transplant of approx. 8.5 million of my own stem cells,” said David.
After 16 days in the hospital following the procedure, David was released to go home to rest and recover before his second stem cell procedure on June 9.
For the Lemley family, participating in this year’s SAA-Seattle has a deeper meaning.
“Now, more than ever, we are committed to raising money for our amazing Fred Hutch Cancer Research Center!” said David.
If you’re inspired to support David and Team InMemory, give here.
1-Mile Swim and 100M Dolphin Dash Take Place December 7 at Daytona International Speedway
CLASH Endurance® and Swim Across America are thrilled to announce a new charity swim in Lake Lloyd, located in the infield of the iconic Daytona International Speedway® on Sunday, Dec. 7, 2025. Participants of all ages will have the opportunity to swim alongside notable Olympians in an inspirational one-mile swim or a 100-meter Dolphin Dash with fundraising for critical cancer research as their top priority. Funds raised will support Swim Across America’s breakthrough pediatric cancer grants with its beneficiaries and CLASH Endurance’s philanthropic partner The NASCAR Foundation.
Swim Across America, founded in 1987, hosts 24 annual open-water swims from Nantucket to under the Golden Gate Bridge, and hundreds and pool swims each year that fund cancer research and patient programs, raising more than $100M to date. Swim Across America has funded transformative trials that led to the FDA-approved immunotherapy cancer medications Keytruda, Opdivo, Yervoy and Tecentriq. The organization has also supported Memorial Sloan Kettering’s landmark trials including the recent Phase II clinical trial published in The New England Journal of Medicine showing an 80% success rate treating MMRd cancers with immunotherapy alone. Swim Across America also recently awarded the first-of-their-kind gene editing innovation grants to Alliance for Cancer Gene Therapy and Dana-Farber Cancer Institute to advance safer, more effective targeted treatments.
“Swim Across America, CLASH Endurance and The NASCAR Foundation joining together makes so much sense as The NASCAR Foundation helps so many kids who are battling cancer,” commented Rob Butcher, CEO of Swim Across America. “To have a Swim Across America charity event in Daytona on the CLASH Endurance Family Weekend means we will make even bigger waves together in the fight against cancer.”
The NASCAR Foundation is a leading charity that works to improve the lives of children who need it most in NASCAR racing communities through the Speediatrics Children’s Fund and the Betty Jane France Humanitarian Award. Serving as a designated 4-Star Charity by Charity Navigator for its strong financial health and ongoing accountability and transparency, it has contributed more than $50 Million to impact the lives of more than 1.7 million children nationwide since 2006.
“We are excited to be a part of the new Swim Across America swim during the CLASH Endurance weekend at Daytona International Speedway. We truly appreciate the many years of support from our friends at CLASH, and it is a privilege to team up again to help improve the health and well-being of kids across the country and in our race communities,” said Nichole Krieger, vice president and executive director of The NASCAR Foundation.
On December 7, when hundreds of swimmers and volunteers dive into Lake Lloyd, one-mile swimmers will be required to raise at least $400 by event day; swimmers under 18 will raise a minimum of $200; Dolphin Dash participants can register for $50 and have no fundraising minimum. To register as a swimmer or a volunteer, visit swimacrossamerica.org/daytona.
CLASH Endurance CEO Bill Christy says, “We are proud to collaborate with Swim Across America which continues to make a lasting impact in the cancer community. This is a cause that has touched all our lives, and we are honored to further support the fight at one of our flagship event weekends.”
Each December when much of the country battles snow, more than 3,000 participants ranging in age from four to 80+ will take on the speedway through a variety of events including a 5K, kids’ triathlon, duathlon, aquabike, triathlons, Test Track and Redline Relay. CLASH Endurance strives to provide a festival-style weekend, which in addition to free activities for spectators and athletes alike, include a wellness expo, food trucks, beer/wine garden and much more. The weekend kicks off with a festive “Jingle Jog 5K” on Friday evening with a start and finish at ONEDaytona. Participants, including those in jogging strollers, will experience Florida’s “Magic of Lights” holiday display taking them under the iconic grandstands of the speedway. The Swim Across America 1-mile swim and Dolphin Dash will help cap-off the weekend on Sunday, December 7.
“We have swum in some incredible venues and Daytona International Speedway is certainly one of the most iconic,” noted Olympic swimmer and Swim Across America Ambassador Rowdy Gaines. “To have a Swim Across America charity swim in Daytona is going to be extra special – I will definitely be there!”
CLASH Endurance® is an innovative endurance event company led by athletes with a passion to provide exceptional race experiences at iconic speedways across the U.S. CLASH embraces inclusion and welcomes athletes of all ages and abilities, from elite professionals to first-time participants. The popular CLASH Endurance DAYTONA event is held at the Daytona International Speedway®, home of ‘The Great American Race”- the Daytona 500, and has been featured on NBC and Fox Sports 1/2. Each February, the Daytona Beach Half Marathon & 5K takes athletes on a scenic tour of Daytona and its numerous landmarks and attractions. In addition, CLASH Endurance Miami in March continues to draw a decorated pro field, collegiate athletes from dozens of prestigious universities and weekend warriors for a challenging course at the historic Homestead-Miami Speedway®. Follow The NASCAR Foundation on Facebook at www.Facebook.com/NASCARFoundation or on X at @NASCAR_FDN. For more information visitclashendurance.com.
Swim Across America hosts open water and pool swims in numerous communities nationwide, from Nantucket to under San Francisco’s Golden Gate Bridge. More than 150 Olympians swim with the organization, including Michael Phelps, Kate Douglass, and Missy Franklin. The organization supports more than 60 cancer research projects annually and has ten named Swim Across America Labs at major institutions nationwide. To learn more, visit swimacrossamerica.org or follow on social media @SwimAcrossAmerica on Facebook and @SAASwim on Instagram.
Doug Bosley has completed some of the most challenging marathon swims in the world, including the cross-continental Hellespont Dardanelles swim, the Maui Channel swim, the Boston Harbor Swim and the St. Croix Reef swim. He has also participated in nearly 30 Swim Across America swims, including Boston and San Francisco.
While those swims were intense, Doug is now facing one of his toughest battles yet: beating acral lentiginous melanoma, a rare form of skin cancer that has sadly spread and metastasized. Despite his diagnosis, Doug’s sense of humor remains intact. He colors his story with anecdotes, punchlines and heartfelt emotion.
“In March 2024, I discovered a very tiny dot on my heel; it was no bigger than an eraser head. So I got it checked out and was diagnosed with a rare form of skin cancer. Not exactly what you want to hear,” Doug shared lightheartedly.
Doug Bosley (back row, center) and Team Festivus at the 2023 Swim Across America – Boston open water swim.
Doug began treatment at Mass General Cancer Center, one of the beneficiaries of the Swim Across America – Boston community swim. The swim also supports Dana-Farber Cancer Institute. Unfortunately, the cancer has quickly progressed and has spread to his liver and brain.
After initial treatments were unsuccessful, Doug was put on BRAF therapy, a combination of medicines that can shrink or slow the growth of metastatic melanoma in those whose tumors have a BRAF mutation. The treatment helped with his liver and lymph nodes but not his brain due to the blood-brain barrier.
He is currently being treated with two immunotherapy medicines – Yervoy and Opdivo – both which received early-stage grant funding from Swim Across America and are FDA approved for treating several different types of cancer.
“I’m doing ok, but the effects of my treatments are taking a toll,” said Doug. “My skin is incredibly sensitive, my feet are swollen to the point where it’s difficult to walk around, my head is foggy, and I have no saliva. But I’m sitting here, employed and engaged to be married – so that’s a good thing.”
Yes, Doug is engaged! After Doug was diagnosed, he proposed to his longtime girlfriend, Laura Lipcsei. The couple splits their time between their house in Somerville, Massachusetts, and the lake cabin they built together in Ontario, Canada.
“I said to Laura, ‘Now is the time to get married because I don’t know where I’ll be in a year,” joked Doug.
In addition to being thankful for Laura, Doug expresses his appreciation for his Swim Across America family, who have supported him through this journey.
Doug, back row center, participated in the 2009 Swim Across America – Boston Harbor swim.
“My Swim Across America family in Boston means everything to me. We started doing the swims as something fun to do together. Somewhere along the way, it became something more emotional. We’d swim, have fun, have a good cry, then come back the next year. Thirty years later and we’re still here,” shared Doug.
One member of Doug’s SAA-Boston swim group has helped him tremendously. Rick Osterberg, who himself is a cancer survivor and also received an immunotherapy pioneered with funding provided by Swim Across America, is Doug’s “cancer coach” and they swim together on Team Festivus.
“So between my wedding, turning 62 and the August 9 SAA-Boston swim, I’ve got a lot to look forward to this summer! I really want to be up there sharing my story with everyone who has supported me this past year.” said Doug.
If you’re inspired to support Doug and Team Festivus, give here.
Read or watch local stories featuring the Swim Across America – Tampa community to learn about their impact. Learn more about the event and beneficiary, Johns Hopkins All Children’s Hospital, at swimacrossamerica.org/tampa.
Shep Jennings is proving that even the youngest swimmers can Make Waves to Fight Cancer! The Darien, Connecticut resident will swim at the 2025 Swim Across America – Fairfield County open water swim on June 21.
Shep Jennings
Shep, who swims year-round with the Darien YMCA Piranhas and in summer with Shorehaven Golf Club, first dove into the charity swim event last year when his swim buddy Jedd Gallagher asked Shep to join the Blue Wave Swim Team, which was participating in the annual Swim Across America – Fairfield County open water swim. The Blue Wave Swim Team was coached by longtime Swim Across America supporter Marj Trifone.
Last summer was the start of a fulfilling experience for Shep, who raised more than $2,000 for the nonprofit in 2024. Seeing his name on the leaderboard last year was inspiring to know he was making a difference.
“I love seeing my name climb the leaderboard, because every dollar means scientists get closer to cures,” said Shep.
The Jennings family
Inspired by watching his parents raise money for ALS research after his grandmother was impacted by the disease, Shep already had the know-how of fundraising down. For Swim Across America, he began emailing friends and family and even going door-to-door in his neighborhood to collect pledges.
Shep, who will turn 12 in September and enter Middlesex Middle School in the fall, acknowledges his favorite summer sports are all about water: swimming, water polo and water-skiing on summer weekends, in the winter, he swaps liquid water for frozen water with snow-skiing. At home he shares the spotlight with his nine-year-old sister, Emmaline, and the family’s golden retriever, Rosie. With just a few weeks left until the big SAA – Fairfield County open water swim, Shep isn’t easing up on his fundraising pace.
Shep, far right, and a few of his teammates
“I’m still reaching out,” he said. “I want my total and the funds for cancer-fighting research to keep growing.” To date, Shep is the number one individual fundraiser already raising $6,080.
The Promising Study Found that 80% of Patients with Mismatch Repair-Deficient (MMRd) Solid Tumors Treated with Immunotherapy Avoided Surgery
The New England Journal of Medicinepublished a paper on April 27, 2025, that presents exciting new results from a clinical trial led by Memorial Sloan Kettering Cancer Center (MSK) gastrointestinal oncologists Andrea Cercek, MD, and Luis Diaz Jr., MD, that demonstrates how immunotherapy alone can help patients with MMRd cancers avoid surgery and preserve their quality of life. The results, presented simultaneously at the 2025 American Association of Cancer Research (AACR) Annual Meeting, showed that 80% of patients with several types of cancer treated with immunotherapy did not require surgery, radiation, or chemotherapy after six months of treatment with immunotherapy alone. Swim Across America awarded grants for the early-stage research and continues to award grants for the ongoing clinical trial.
Andrea Cercek, M.D., gastrointestinal oncologist and co-director of the Center for Young Onset Colorectal and Gastrointestinal Cancer at Memorial Sloan Kettering Cancer Center
Mismatch repair deficiency (MMRd) in cancer refers to a situation where tumor cells have defective mismatch repair (MMR) proteins, essential for correcting DNA errors during cell replication. This deficiency leads to the accumulation of mutations, including microsatellite instability (MSI), making tumors more prone to be recognized by the immune system. MMRd status is a significant factor in cancer treatment, particularly for immunotherapy, as it can predict response to immune checkpoint inhibitors.
The standard of care for many cancers that have this specific MMRd genetic mutation has been surgery, radiation, and chemotherapy. Still, the patients who responded positively to this clinical trial did not require surgery to remove an organ and did not experience chemotherapy or radiation, which improved their quality of life. This trial is the first time that immunotherapy has been shown to replace surgery for a variety of solid tumors.
“This study shows that immunotherapy can replace surgery, radiation and chemotherapy for mismatch repair-deficient solid tumors, which could help patients preserve their organs and avoid the harsh side effects of chemo and radiation,” said Andrea Cercek, M.D., gastrointestinal oncologist and co-director of the Center for Young Onset Colorectal and Gastrointestinal Cancer at Memorial Sloan Kettering Cancer Center. “Preserving a patient’s quality of life, while also successfully achieving positive results in eliminating their cancer, is the best possible outcome. They can return to their daily routines and maintain their independence.”
Luis Diaz, M.D., gastrointestinal oncologist and Head of the Division of Solid Tumor Oncology at Memorial Sloan Kettering Cancer Center
This phase 2 trial is an extension of a groundbreaking study, also funded in part by Swim Across America, in which all rectal cancer patients treated with the immunotherapy dostarlimab experienced a complete clinical response, meaning their tumors disappeared. This was the first time ever that a clinical trial had a 100% positive response rate.
The updated trial included 103 patients with stage 1-3 cancer; 49 with rectal cancer; and 54 with non-rectal cancers, including gastroesophageal, hepatobiliary, colon, genitourinary, and gynecologic. Drs. Cercek and Diaz noted that the 80% response rate in this expanded clinical trial is very exciting for these types of cancer.
“Grants provided by Swim Across America were critical to our initial study and advancing this trial to phase 2,” said Luis Diaz, M.D., gastrointestinal oncologist and Head of the Division of Solid Tumor Oncology at Memorial Sloan Kettering Cancer Center.
Founded in 1987, Swim Across America has raised more than $100 million to fight cancer. In its 38 years of making waves, thousands of volunteers and Olympians have swum the circumference of the earth three times uniting a movement to fight cancer that has created a groundswell of support spanning all generations. Today, more than 24 communities across the U.S. hold charity swims each year, which support innovative cancer research, detection, and patient programs.
Drs. Andrea Cercek and Luis Diaz spoke at the 2024 Swim Across America – Long Island Sound open water swim
Swim Across America’s funding of clinical trials on a national level has helped contribute to four FDA-approved life-saving immunotherapy cancer treatments: Yervoy, Opdivo, Tecentriq, and Keytruda. Swim Across America awards grant to more than 60 projects each year and there are ten named Swim Across America Labs at major institutions.
In addition to Swim Across America grants, this trial received funding from the National Institutes of Health, National Cancer Institute, Haystack Oncology, and Stand Up To Cancer. MSK also acknowledges support from GSK, whose PD-1 blockade Jemperli (dostarlimab), represents a promising advancement in the treatment of patients.
For more information and to inquire about eligibility for this clinical trial, talk to your oncologist or call MSK at 646-888-4189. You may also reach to info@swimacrossamerica.org and we will help guide you.
Choi’s next generation CAR-T therapy, funded in part by SAA-Boston and SAA-Nantucket, has shown “dramatic and rapid” regression of glioblastoma
With early funding from Swim Across America – Boston and Swim Across America – Nantucket, Dr. Bryan Choi’s research on tandem CAR T-cell therapy for ependymoma was approved for a Phase I trial. The first human patient was infused at the end of April 2023. The results of the first human trials, as described in 2024 by the New England Journal of Medicine, showed “dramatic and rapid” regression of glioblastoma.
In an exclusive briefing to Swim Across America participants, Dr. Bryan Choi, a neurosurgeon and neuro-oncologist at Massachusetts General Cancer Center, delivered an update on his research path.
From left, brain tumors, marked by red and green arrows, disappear a day after CAR-T immunotherapy treatment. From CNN.
The Swim Across America lab visit included not only highlights from on the ongoing Phase I trial, but also a few first-hand stories about the life-changing impacts of the new CAR-T cell therapy for one of the patients, who has chosen to share his story publicly.
Tom Fraser (Patient #2) has shared his story publicly with news outlets that include CNN and New York Magazine.
Tom Fraser, 72, (center, in the blue shirt) was treated with a single infusion of CAR-T cells. Two days later, an MRI showed a decrease in the tumor’s size by 18.5 percent. By day 69, the tumor had decreased by 60.7 percent, and the response was sustained for over 6 months. From The Harvard Gazette.
CAR T-cell therapy, a type of gene therapy that engineers a patient’s own T-cells (a type of white blood cells) to identify and attack cancer cells by way of their antigen markers, has shown promise in the treatment of blood cancers. The research team created dual antigen-targeting tandem CAR T (TanCART) cells to target heterogeneous solid tumors. Dr. Choi’s research shows that this type of therapy can also be manipulated to treat solid tumors like ependymoma.
At the suggestion of Dr. Howard Weinstein, Unit Chief of Pediatric Hematology/Oncology at Mass General for Children and long-time Swim Across America partner, Dr. Choi applied for a Swim Across America research grant through the internal competitive bid program at Mass General for Children.
Dr. Choi recruiting the next generation of researchers, like SAA – Nantucket supporter, Braden Hussey.
Without the Swim Across America grant, Dr. Choi said, his research likely would have remained unfunded, and neither the FDA approval nor the Phase I Study approval, which is funded by industry investors, would have been possible.
Janel Jorgensen McArdle, Chief Operating Officer of Swim Across America, pointed out that Dr. Choi’s research falls in the “sweet spot” of the high risk, high reward research that Swim Across America is pursuing.
“This promising research aligned perfectly with the opportunities that Swim Across America seeks to support,” said McArdle. “We are so excited that SAA funding could help accelerate it to patient trials – and are thrilled to see the benefits to patients!”
Dr. Choi explained CAR-T cell therapy to the Swim Across America group on April 4, 2025.
After his highly informative presentation, Dr. Choi gave the Swim Across America group a private tour of his lab spaces, which were in the finishing stages of build-out when they toured two years ago.
The group also got to visit the Ether Dome at Mass General, the surgical amphitheater where, in 1846, the first public surgery with anesthesia was performed.
It was an exciting visit for Swim Across America news and for all of the Swim Across America – Boston and Nantucket supporters who were present!
Swim Across America lab visit participants, pictured with Dr. Choi in the Ether Dome at Mass General, site of the first use of anesthesia in public surgery.
Revolutionary CRISPR Gene Editing and Other Cell and Gene Therapy Editing Takes Center Stage in Finding Ways to Effectively Treat Cancer
Swim Across America, the nonprofit funding innovative clinical trials and patient-centered programs for cancer,is proud to announce the award of two $450,000 grants to two of its beneficiaries, Alliance for Cancer Gene Therapy(ACGT) and Dana-Farber Cancer Institute, to support the work of novel gene and base editing techniques used in advanced cancer research, including targeted therapies, immunotherapies and cellular therapies. The two-year grants will specifically support the work of scientific investigators Joseph Fraietta, PhD, at the University of Pennsylvania through ACGT, and Pietro Genovese, PhD, at Dana-Farber Cancer Institute, for their work in groundbreaking cell and gene therapy cancer research. This financial support paves the way for more effective therapies across many cancer types including solid tumors, offering potential new hope for patients with hard to treat cancer types or limited treatment options.
“Gene editing, including CRISPR, are some of the most promising frontiers in cancer research allowing for advances in targeted therapies, immunotherapies, CAR-T cell therapy and early/minimal residual disease detection, diagnostics and cancer vaccines,” said Rob Butcher, CEO of Swim Across America. “These grants to Dr. Fraietta through ACGT, and Dr. Genovese at Dana-Farber, will help accelerate the advancement of potential gene-edited cancer treatments that could transform how we treat patients and their quality of life. Just as our previous funding has helped develop immunotherapy treatments that are saving lives today, we believe these pointed investments will help accelerate the next generation of cancer breakthroughs.”
Joseph Fraietta, PhD
Joseph Fraietta, PhD, through Swim Across America–Fairfield County beneficiary Alliance for Cancer Gene Therapy, is developing an innovative “off-the-shelf” cell therapy for aggressive cancers. His research uses a precise gene-editing tool called a “base editor” to create more effective CAR T cells that can target cancers with KRAS mutations, found in 20-25% of all cancers including lung, colon and pancreatic cancer. His team is also developing “micropharmacies” – immune cells engineered to release powerful cancer-fighting signals directly at tumor sites while minimizing side effects.
Pietro Genovese, PhD
Pietro Genovese, PhD, at Dana-Farber, is taking a revolutionary approach to treating acute myeloid leukemia (AML). Rather than targeting cancer cells directly, his team is creating “stealth” healthy blood cells engineered to survive cancer treatments while allowing the selective elimination of cancer cells. This innovative strategy could provide less toxic treatment options for AML and other blood cancers where traditional therapies often harm healthy cells along with cancerous ones.
“With the current funding landscape and resources potentially constrained, nonprofit organizations play a vital role in ensuring innovative cancer research moves forward,” said Evan Vosburgh, MD, Research and Grants committee chair for Swim Across America. “These targeted grants support precisely the kind of high-risk, high-reward research that could revolutionize cancer treatment, but might otherwise go unfunded. By supporting early-stage research in cell and gene therapy, we’re helping bridge critical funding gaps and accelerating the development of potentially life-saving treatments.”
Swim Across America has raised more than $100 million for cancer research since its founding in 1987 and has a strong track record of funding transformative research, including clinical trials that led to FDA-approved immunotherapy medicines Keytruda, Opdivo, Yervoy and Tecentriq. The organization was also a grant funder of Memorial Sloan Kettering’s landmark clinical trial that achieved a 100% success rate treating advanced rectal cancer patients with dostarlimab.
About Swim Across America Swim Across America hosts open water and pool swims in numerous communities nationwide, from Nantucket to under San Francisco’s Golden Gate Bridge. More than 150 Olympians support the organization, including Michael Phelps, Kate Douglass, Missy Franklin and Ryan Lochte. The organization supports more than 60 cancer research projects annually and has ten named Swim Across America Labs at major institutions nationwide. To learn more visit swimacrossamerica.org or follow on social media @SwimAcrossAmerica on Facebook and @SAASwim on Instagram.
Read or watch local stories featuring the Swim Across America-Nashville community to learn about their impact. Learn more about the event and beneficiary, Vanderbilt-Ingram Cancer Center, at swimacrossamerica.org/nashville.
Swim Across America 