Tag: News

Kelly Lennon: A Full Circle Journey with Swim Across America

Posted on Posted in #DefeatCancer, #MakingWavesToFightCancer, #SwimAcrossAmerica, Family Tree, Fundraising, Nassau/Suffolk - Sound to Cove, Pool SwimsTagged , , , , , , , 1 Comment

From a young age, Kelly Lennon was always driven to make an impact in her community. In high school, Kelly swam with her school team and joined Swim Across America – Nassau/Suffolk. Nearly a decade later, Kelly returned to Swim Across America as a coach and helped raise more than $40,000.

“In December 2016, I was honored for my fundraising efforts with a Proclamation from the Town of Huntington, New York, by Legislator Susan Berland,” shared Kelly. “After I graduated high school, I knew I’d come back to Swim Across America because it was that important to me.”

Kelly may have physically “left” for college, but her passion for Swim Across America still tugged at her heart. It wasn’t until eight years later that Kelly found her way back to Swim Across America to rejoin the fight to cure cancer. 

“I graduated from college and took a job at the Huntington YMCA coaching an age group team called the Bluefish,” shared Kelly. “I couldn’t wait to bring my joy for SAA to this new bunch of kids in our community.”

With the help of the SAA National and SAA-Nassau/Suffolk local committee, Kelly started the Huntington Y Bluefish SAA Pool Swim. Together, the team quickly exceeded their original $10,000 goal and raised over $40,000 for their beneficiaries: Memorial Sloan Kettering Cancer Center, Weill Cornell Medicine, Cold Spring Harbor Laboratory, the Feinstein Institute at Northwell Health, MD Anderson Children’s Cancer Hospital, and SHARE Cancer Support.  

“What a full circle moment for me! Supporting this organization as an adult, with my team of young swimmers, brought back so many memories,” said Kelly.

The fight to find a cure never changed, but Kelly’s personal growth over eight years fed her passion and fueled her fire to fight cancer. 

“I support Swim Across America because cancer has deeply affected my family. Some of my loved ones have survived, while others have, sadly, passed away,” shared Kelly.

“I swim in memory of those we’ve lost and in support of those still fighting. This cause is personal to me—every stroke is a tribute to their strength, courage, and the hope that, through continued research, we can find better treatments and ultimately a cure. That’s what motivates me to raise funds and be part of this incredible community.” 

Swim Across America grants have had incredible success, particularly at Memorial Sloan Kettering Cancer Center, one of the SAA-Nassau/Suffolk beneficiaries. The community is a grant funder of MSK’s landmark clinical trial that achieved a 100% success rate treating advanced rectal cancer patients with dostarlimab; as well as a funder of the most recent Phase II clinical trial at MSK just published in The New England Journal of Medicine that showed an 80% success rate in treating patients with several types of MMRd cancers who were treated with immunotherapy and did not require surgery, radiation, or chemotherapy after six months of treatment with immunotherapy alone. SAA awarded the grants for the early-stage research and continues to award grants for the ongoing clinical trial. 

Seeing the impact SAA has on cancer research is what drives Kelly to continue to support the mission. 

“Swim Across America makes a real impact by funding innovative cancer research and clinical trials that give patients hope and save lives,” said Kelly. 

“It’s important to me and my family because it turns grief into action and brings people together to fight for a future without cancer.”

If you are moved to support Kelly and Huntington Y Bluefish, click here.

From Survivor to Swimmer: 13-Year-Old Cancer Survivor Jane Hatch Makes Waves for Pediatric Cancer Research

Posted on Posted in #MakingWavesToFightCancer, #SwimAcrossAmerica, beneficiaries, Events, Family Tree, Fundraising, Long Island Sound, Making Waves With Hope, Pool SwimsTagged , , , , , , , 1 Comment

When 13-year-old leukemia survivor Jane Hatch dives into one of this summer’s Swim Across America – Long Island Sound pool swims at Westchester County Country Club on July 12, she’ll be carrying on a family legacy that began more than three decades ago. Her grandfather, Frank Webers, helped launch the very first SAA – Long Island Sound charity swim in 1992 after sadly losing his wife, Kathleen “Kathy” Webers, to brain cancer at just 42. Only 17 swimmers took to the water that inaugural year. Today the event draws 800+ participants and is the largest Swim Across America event in the country, raising millions for cancer research and patient care.

Jane Hatch, a young leukemia survivor, will swim at a SAA-Long Island Sound pool swim this year.

Jane’s mother, June, is one of three daughters of Frank and Kathy Webers – April, May and June. While cancer has thankfully skipped her mother’s generation, Jane was diagnosed with leukemia at just six years old. Throughout the past seven years and through her treatment years, Jane has participated in supporting SAA – Long Island Sound any way she could – by selling lemonade and bake sales, and in 2019, her Mom June swam in her honor.

This year, Jane will swim in the Westchester Country Club pool swim on July 12. Her family has been comforted in knowing that a portion of the funds raised through SAA – Long Island Sound are going directly to Memorial Sloan Kettering, where Jane was treated.

“Jane is thriving because of breakthrough science and compassionate care, some of which has been funded directly through Swim Across America,” said June  Hatch, Jane’s mother and member of Team Jane.  “We swim, volunteer and donate to fund the next breakthroughs — especially for children who still face cancer with far fewer treatment options than adults.”

Only 4% of federal cancer-research dollars target childhood cancers. Swim Across America – Long Island Sound is hoping to change that and is directing 20% of proceeds from its open water and eight pool swims this year to pediatric-cancer research at Memorial Sloan Kettering Kids and NewYork-Presbyterian Children’s Hospital through its KIDS Swimming FOR KIDS program.

To raise awareness and inspire young swimmers, Swim Across America will be offering a fun buy-one, give-one campaign offering supporters a chance to get a Dash the Dolphin, Swim Across America’s mascot’s plush toy for a $30 donation — for each plush toy purchased, a second plush toy will be gifted to a pediatric cancer patient at Memorial Sloan Kettering Kids and NewYork-Presbyterian Children’s Hospital through the swim’s KIDS Swimming FOR KIDS program.

From Heartbreak to Hope: Team Gina Makes Waves to Fight Cancer

Posted on Posted in #DefeatCancer, #MakingWavesToFightCancer, #SwimAcrossAmerica, beneficiaries, Events, Fundraising, Long Island Sound, Messages of Hope, Pool Swims, UncategorizedTagged , , , , , , , 1 Comment

Almost a year-and-a-half after sadly losing Gina Mannix Wente to breast cancer, who was just 32-years-old and a beloved wife, mother, daughter and sister, more than 50 of her relatives and friends are suiting up again to make a big splash with “Team Gina” at the 33rd annual Swim Across America – Long Island Sound open water swim on Saturday, July 26, held on the shores of Long Island Sound in Larchmont, New York.

Gina Mannix Wente

The team has hit the ground running and is already one of the top fundraising teams, raising $33,255 to date for the July charity swim. For Team Gina, diving back into the water isn’t just a tribute – it’s a way to keep Gina’s competitive spirit and generosity alive – all while fueling cancer research that could help others battle this terrible disease.

Gina grew up swimming at the Larchmont Shore Club, captained undefeated squads at Ursuline and the College of the Holy Cross, and later coached for the New York Athletic Club. She balanced that passion with a finance career that took her to GE Capital and Ferrara Candy. In 2021 she married Dave Wente. Their daughter, McKenzie, arrived in 2022, and their son, David Charles, was delivered early at just 29 weeks on February 1, 2024, weeks after Gina’s sudden cancer diagnosis. Gina sadly passed away on February 26, 2024, just 3-1/2 weeks after welcoming her son.

Gina and her daughter, McKenzie

“Last summer’s swim, was as you can imagine, raw and emotional for all of us after losing Gina so suddenly,” noted Gina’s mother, Mary Mannix. “However, being all together at the swim and doing something that Gina loved was also very healing. We are coming back this year stronger and more energized than ever before. Every dollar we raise honors her love of the sport of swimming and helps fund the breakthroughs that can possibly help save other lives.”

“Cancer knows no boundaries,” noted Jean Fufidio, event director for SAA-Long Island Sound. “It impacts adults, young adults and children. Diagnoses of young adults globally have risen by 79%. But here’s how Swim Across America Long Island Sound is making a positive impact. A recent Time Magazine story, ‘The Race to Explain Why More Young Adults are Getting Cancer’ mentioned the ground-breaking, rectal clinical trials done by one of our very own fellow doctors, with a 100% response rate. A subsequent trial that was expanded to other gastrointestinal MMRd type cancers and published in The New England Journal of Medicine in April showed an astounding 80% success rate with immunotherapy alone – no surgery, chemotherapy or radiation. That is making an impact.”

Members of Team Gina swam at the 2024 SAA-Long Island Sound open water swim

Proceeds from SAA-Long Island Sound benefit Swim Across America’s local beneficiaries: Memorial Sloan Kettering Cancer Center, Columbia University Medical Center, Cancer Support Team and Weill Cornell Medicine. Registration, volunteer sign-ups and donations are open at swimacrossamerica.org/longislandsound.

Now in its 33rd year, SAA-Long Island Sound open water and pool swims have contributed nearly $30 million towards cancer research, resulting in FDA approved immunotherapy treatments of Keytruda, Opdivo and Yervoy. What’s more is the money raised locally stays local, providing cancer care and research grants to The Cancer Support Team, a Westchester-based home care program offering free services to patients and their families; to New York Presbyterian Children’s Hospital Pediatric Oncology Lab; to Memorial Sloan-Kettering Research Laboratories of Dr. Diaz and Dr. Kung Kids Department of Pediatrics; and to Weill Cornell Medicine Research Laboratory of Dr. Wolchok and Dr. Merghoub.

SWIM ACROSS AMERICA – FAIRFIELD COUNTY IN THE NEWS

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Read or watch local stories featuring the Swim Across America – Fairfield County community to learn about their impact. Learn more about the event and beneficiary, Alliance for Cancer Gene Therapy, at swimacrossamerica.org/fc.

SAASWIM.COM – Swim Across America blog

11-Year-Old Shep Jennings Makes Big Waves to Fight Cancer

News 12 Connecticut

Swim Across America Fairfield County raises $400,000 for cancer research

WABC-TV (ABC, 7) NY

Swim Across America – Fairfield County Open Water Swim

Darien Magazine CT

Crazy for the Swim

Darien Patch

11 Year-Old Darien Resident Shep Jennings is Making Waves to Fight Cancer

Darien Daily Voice

From Pool To Podium: Darien Boy, 11, Raises Thousands For Research While Chasing Olympic Dream

Greenwich Daily Voice

From Pool To Podium: Darien Boy, 11, Raises Thousands For Research While Chasing Olympic Dream

Greenwich Free Press

Swim Across America Fairfield County Fundraiser at Bosco’s Bar & Grill to Feature MOJO

19th Annual Swim Across America – Fairfield County Open Water Swim Swim Raises $400,000 for Cancer Research

Greenwich Patch

Greenwich Family Raises Money For Groups That Helped Girl With Cancer

Living Greenwich

Make Waves to Fight Cancer at the 19th Annual Swim Across America Fairfield County

Stamford Patch

Mole Mavens Provide On-Site Mole Checks at June 21 Swim Across America – Fairfield County Open Water Swim

Sunny Skies Forecast for Saturday’s Swim Across America – Fairfield County

Swim with a Purpose: CLASH Endurance Announces New Charity Swim Events with Swim Across America

Posted on Posted in #DefeatCancer, #MakingWavesToFightCancer, #SwimAcrossAmerica, beneficiaries, Clash Endurance, daytona, Events, Making Waves With Hope, NASCAR, News, partnershipsTagged , , , , , , , , , , 1 Comment

1-Mile Swim and 100M Dolphin Dash Take Place December 7 at Daytona International Speedway

CLASH Endurance® and Swim Across America are thrilled to announce a new charity swim in Lake Lloyd, located in the infield of the iconic Daytona International Speedway® on Sunday, Dec. 7, 2025. Participants of all ages will have the opportunity to swim alongside notable Olympians in an inspirational one-mile swim or a 100-meter Dolphin Dash with fundraising for critical cancer research as their top priority. Funds raised will support Swim Across America’s breakthrough pediatric cancer grants with its beneficiaries and CLASH Endurance’s philanthropic partner The NASCAR Foundation.

Swim Across America, founded in 1987, hosts 24 annual open-water swims from Nantucket to under the Golden Gate Bridge, and hundreds and pool swims each year that fund cancer research and patient programs, raising more than $100M to date. Swim Across America has funded transformative trials that led to the FDA-approved immunotherapy cancer medications Keytruda, Opdivo, Yervoy and Tecentriq. The organization has also supported Memorial Sloan Kettering’s landmark trials including the recent Phase II clinical trial published in The New England Journal of Medicine showing an 80% success rate treating MMRd cancers with immunotherapy alone. Swim Across America also recently awarded the first-of-their-kind gene editing innovation grants to Alliance for Cancer Gene Therapy and Dana-Farber Cancer Institute to advance safer, more effective targeted treatments.

“Swim Across America, CLASH Endurance and The NASCAR Foundation joining together makes so much sense as The NASCAR Foundation helps so many kids who are battling cancer,” commented Rob Butcher, CEO of Swim Across America. “To have a Swim Across America charity event in Daytona on the CLASH Endurance Family Weekend means we will make even bigger waves together in the fight against cancer.”

The NASCAR Foundation is a leading charity that works to improve the lives of children who need it most in NASCAR racing communities through the Speediatrics Children’s Fund and the Betty Jane France Humanitarian Award. Serving as a designated 4-Star Charity by Charity Navigator for its strong financial health and ongoing accountability and transparency, it has contributed more than $50 Million to impact the lives of more than 1.7 million children nationwide since 2006.

“We are excited to be a part of the new Swim Across America swim during the CLASH Endurance weekend at Daytona International Speedway. We truly appreciate the many years of support from our friends at CLASH, and it is a privilege to team up again to help improve the health and well-being of kids across the country and in our race communities,” said Nichole Krieger, vice president and executive director of The NASCAR Foundation.

On December 7, when hundreds of swimmers and volunteers dive into Lake Lloyd, one-mile swimmers will be required to raise at least $400 by event day; swimmers under 18 will raise a minimum of $200; Dolphin Dash participants can register for $50 and have no fundraising minimum. To register as a swimmer or a volunteer, visit swimacrossamerica.org/daytona.

CLASH Endurance CEO Bill Christy says, “We are proud to collaborate with Swim Across America which continues to make a lasting impact in the cancer community. This is a cause that has touched all our lives, and we are honored to further support the fight at one of our flagship event weekends.”

Each December when much of the country battles snow, more than 3,000 participants ranging in age from four to 80+ will take on the speedway through a variety of events including a 5K, kids’ triathlon, duathlon, aquabike, triathlons, Test Track and Redline Relay. CLASH Endurance strives to provide a festival-style weekend, which in addition to free activities for spectators and athletes alike, include a wellness expo, food trucks, beer/wine garden and much more. The weekend kicks off with a festive “Jingle Jog 5K” on Friday evening with a start and finish at ONEDaytona. Participants, including those in jogging strollers, will experience Florida’s “Magic of Lights” holiday display taking them under the iconic grandstands of the speedway. The Swim Across America 1-mile swim and Dolphin Dash will help cap-off the weekend on Sunday, December 7.

“We have swum in some incredible venues and Daytona International Speedway is certainly one of the most iconic,” noted Olympic swimmer and Swim Across America Ambassador Rowdy Gaines. “To have a Swim Across America charity swim in Daytona is going to be extra special – I will definitely be there!”

CLASH Endurance® is an innovative endurance event company led by athletes with a passion to provide exceptional race experiences at iconic speedways across the U.S. CLASH embraces inclusion and welcomes athletes of all ages and abilities, from elite professionals to first-time participants. The popular CLASH Endurance DAYTONA event is held at the Daytona International Speedway®, home of ‘The Great American Race”- the Daytona 500, and has been featured on NBC and Fox Sports 1/2. Each February, the Daytona Beach Half Marathon & 5K takes athletes on a scenic tour of Daytona and its numerous landmarks and attractions. In addition, CLASH Endurance Miami in March continues to draw a decorated pro field, collegiate athletes from dozens of prestigious universities and weekend warriors for a challenging course at the historic Homestead-Miami Speedway®. Follow The NASCAR Foundation on Facebook at www.Facebook.com/NASCARFoundation or on X at @NASCAR_FDN. For more information visit clashendurance.com.

Swim Across America hosts open water and pool swims in numerous communities nationwide, from Nantucket to under San Francisco’s Golden Gate Bridge. More than 150 Olympians swim with the organization, including Michael Phelps, Kate Douglass, and Missy Franklin. The organization supports more than 60 cancer research projects annually and has ten named Swim Across America Labs at major institutions nationwide. To learn more, visit swimacrossamerica.org or follow on social media @SwimAcrossAmerica on Facebook and @SAASwim on Instagram.

Doug Bosley: From Marathon Swims to His Toughest Challenge Yet

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Doug Bosley has completed some of the most challenging marathon swims in the world, including the cross-continental Hellespont Dardanelles swim, the Maui Channel swim, the Boston Harbor Swim and the St. Croix Reef swim. He has also participated in nearly 30 Swim Across America swims, including Boston and San Francisco. 

While those swims were intense, Doug is now facing one of his toughest battles yet: beating acral lentiginous melanoma, a rare form of skin cancer that has sadly spread and metastasized. Despite his diagnosis, Doug’s sense of humor remains intact. He colors his story with anecdotes, punchlines and heartfelt emotion. 

“In March 2024, I discovered a very tiny dot on my heel; it was no bigger than an eraser head. So I got it checked out and was diagnosed with a rare form of skin cancer. Not exactly what you want to hear,” Doug shared lightheartedly. 

Doug Bosley (back row, center) and Team Festivus at the 2023 Swim Across America – Boston open water swim.

Doug began treatment at Mass General Cancer Center, one of the beneficiaries of the Swim Across America – Boston community swim. The swim also supports Dana-Farber Cancer Institute. Unfortunately, the cancer has quickly progressed and has spread to his liver and brain. 

After initial treatments were unsuccessful, Doug was put on BRAF therapy, a combination of medicines that can shrink or slow the growth of metastatic melanoma in those whose tumors have a BRAF mutation. The treatment helped with his liver and lymph nodes but not his brain due to the blood-brain barrier.

He is currently being treated with two immunotherapy medicines – Yervoy and Opdivo – both which received early-stage grant funding from Swim Across America and are FDA approved for treating several different types of cancer.

“I’m doing ok, but the effects of my treatments are taking a toll,” said Doug. “My skin is incredibly sensitive, my feet are swollen to the point where it’s difficult to walk around, my head is foggy, and I have no saliva. But I’m sitting here, employed and engaged to be married – so that’s a good thing.”

Yes, Doug is engaged! After Doug was diagnosed, he proposed to his longtime girlfriend, Laura Lipcsei. The couple splits their time between their house in Somerville, Massachusetts, and the lake cabin they built together in Ontario, Canada. 

“I said to Laura, ‘Now is the time to get married because I don’t know where I’ll be in a year,” joked Doug. 

In addition to being thankful for Laura, Doug expresses his appreciation for his Swim Across America family, who have supported him through this journey. 

Doug, back row center, participated in the 2009 Swim Across America – Boston Harbor swim.

“My Swim Across America family in Boston means everything to me. We started doing the swims as something fun to do together. Somewhere along the way, it became something more emotional. We’d swim, have fun, have a good cry, then come back the next year. Thirty years later and we’re still here,” shared Doug.  

One member of Doug’s SAA-Boston swim group has helped him tremendously. Rick Osterberg, who himself is a cancer survivor and also received an immunotherapy pioneered with funding provided by Swim Across America, is Doug’s “cancer coach” and they swim together on Team Festivus. 

“So between my wedding, turning 62 and the August 9 SAA-Boston swim, I’ve got a lot to look forward to this summer! I really want to be up there sharing my story with everyone who has supported me this past year.” said Doug. 

If you’re inspired to support Doug and Team Festivus, give here.

SWIM ACROSS AMERICA – TAMPA BAY IN THE MEDIA

Posted on Posted in #DefeatCancer, #MakingWavesToFightCancer, #SwimAcrossAmerica, beneficiaries, Events, Family Tree, Fundraising, Making Waves With Hope, Messages of Hope, News, tampa, UncategorizedTagged , , , , , , Leave a comment

Read or watch local stories featuring the Swim Across America – Tampa community to learn about their impact. Learn more about the event and beneficiary, Johns Hopkins All Children’s Hospital, at swimacrossamerica.org/tampa.

SWIM ACROSS AMERICA BLOG – SAASWIM.COM

Swim Across America – Tampa Bay Welcomes a Family That Makes Waves to Fight Cancer Together

WTVT-TV (FOX, 13)

Swimming for a cause

11-year-old takes on Swim Across America challenge in support of older sister

Spectrum News Bay News 9

Cancer survivors cheer on their biggest fans at Swim Across America

St. Pete family affected by cancer swims to raise funds

St. Pete Catalyst

St. Pete sister swims Saturday for cancer research

Bloom Tampa Bay

Making Waves Against Cancer: How two sisters battle cancer with Swim Across America

iHeartRadio WFLA-AM/FM

“The Ryan Gorman Show” + “What’s Happening Around Town this Weekend” with Sharon Wynne tampabay.com

Swim Across America Grant Funding of Memorial Sloan-Kettering Cancer Center Clinical Trial Shows that Immunotherapy Alone Could Replace Surgery, Enabling Patients to Retain Their Organs and Enhance Their Quality of Life 

Posted on Posted in #DefeatCancer, #MakingWavesToFightCancer, #SwimAcrossAmerica, AACR, beneficiaries, Events, Fundraising, Grant, Long Island Sound, Making Waves With Hope, Messages of Hope, Nassau/Suffolk - Sound to Cove, NewsTagged , , , , , , , , Leave a comment

The Promising Study Found that 80% of Patients with Mismatch Repair-Deficient (MMRd) Solid Tumors Treated with Immunotherapy Avoided Surgery 

The New England Journal of Medicine published a paper on April 27, 2025, that presents exciting new results from a clinical trial led by Memorial Sloan Kettering Cancer Center (MSK) gastrointestinal oncologists Andrea Cercek, MD, and Luis Diaz Jr., MD, that demonstrates how immunotherapy alone can help patients with MMRd cancers avoid surgery and preserve their quality of life. The results, presented simultaneously at the 2025 American Association of Cancer Research (AACR) Annual Meeting, showed that 80% of patients with several types of cancer treated with immunotherapy did not require surgery, radiation, or chemotherapy after six months of treatment with immunotherapy alone. Swim Across America awarded grants for the early-stage research and continues to award grants for the ongoing clinical trial.

Andrea Cercek, M.D., gastrointestinal oncologist and co-director of the Center for Young Onset Colorectal and Gastrointestinal Cancer at Memorial Sloan Kettering Cancer Center

Mismatch repair deficiency (MMRd) in cancer refers to a situation where tumor cells have defective mismatch repair (MMR) proteins, essential for correcting DNA errors during cell replication. This deficiency leads to the accumulation of mutations, including microsatellite instability (MSI), making tumors more prone to be recognized by the immune system. MMRd status is a significant factor in cancer treatment, particularly for immunotherapy, as it can predict response to immune checkpoint inhibitors. 

The standard of care for many cancers that have this specific MMRd genetic mutation has been surgery, radiation, and chemotherapy. Still, the patients who responded positively to this clinical trial did not require surgery to remove an organ and did not experience chemotherapy or radiation, which improved their quality of life. This trial is the first time that immunotherapy has been shown to replace surgery for a variety of solid tumors. 

“This study shows that immunotherapy can replace surgery, radiation and chemotherapy for mismatch repair-deficient solid tumors, which could help patients preserve their organs and avoid the harsh side effects of chemo and radiation,” said Andrea Cercek, M.D., gastrointestinal oncologist and co-director of the Center for Young Onset Colorectal and Gastrointestinal Cancer at Memorial Sloan Kettering Cancer Center. “Preserving a patient’s quality of life, while also successfully achieving positive results in eliminating their cancer, is the best possible outcome. They can return to their daily routines and maintain their independence.”

Luis Diaz, M.D., gastrointestinal oncologist and Head of the Division of Solid Tumor Oncology at Memorial Sloan Kettering Cancer Center

This phase 2 trial is an extension of a groundbreaking study, also funded in part by Swim Across America, in which all rectal cancer patients treated with the immunotherapy dostarlimab experienced a complete clinical response, meaning their tumors disappeared. This was the first time ever that a clinical trial had a 100% positive response rate.

The updated trial included 103 patients with stage 1-3 cancer; 49 with rectal cancer; and 54 with non-rectal cancers, including gastroesophageal, hepatobiliary, colon, genitourinary, and gynecologic. Drs. Cercek and Diaz noted that the 80% response rate in this expanded clinical trial is very exciting for these types of cancer.

“Grants provided by Swim Across America were critical to our initial study and advancing this trial to phase 2,” said Luis Diaz, M.D., gastrointestinal oncologist and Head of the Division of Solid Tumor Oncology at Memorial Sloan Kettering Cancer Center.

Founded in 1987, Swim Across America has raised more than $100 million to fight cancer. In its 38 years of making waves, thousands of volunteers and Olympians have swum the circumference of the earth three times uniting a movement to fight cancer that has created a groundswell of support spanning all generations. Today, more than 24 communities across the U.S. hold charity swims each year, which support innovative cancer research, detection, and patient programs. 

Drs. Andrea Cercek and Luis Diaz spoke at the 2024 Swim Across America – Long Island Sound open water swim

Swim Across America’s funding of clinical trials on a national level has helped contribute to four FDA-approved life-saving immunotherapy cancer treatments: Yervoy, Opdivo, Tecentriq, and Keytruda. Swim Across America awards grant to more than 60 projects each year and there are ten named Swim Across America Labs at major institutions.

In addition to Swim Across America grants, this trial received funding from the National Institutes of Health, National Cancer Institute, Haystack Oncology, and Stand Up To Cancer. MSK also acknowledges support from GSK, whose PD-1 blockade Jemperli (dostarlimab), represents a promising advancement in the treatment of patients.

For more information and to inquire about eligibility for this clinical trial, talk to your oncologist or call MSK at 646-888-4189. You may also reach to info@swimacrossamerica.org and we will help guide you. 

Swim Across America Presentation and Lab Visit with researcher, Bryan Choi MD, PhD

Posted on Posted in #DefeatCancer, #MakingWavesToFightCancer, #SwimAcrossAmerica, beneficiaries, boston, event directors, Events, Grant, Labs, Making Waves With Hope, Messages of Hope, nantucketTagged , , , , , , , Leave a comment

Choi’s next generation CAR-T therapy, funded in part by SAA-Boston and SAA-Nantucket, has shown “dramatic and rapid” regression of glioblastoma

With early funding from Swim Across America – Boston and Swim Across America – Nantucket, Dr. Bryan Choi’s research on tandem CAR T-cell therapy for ependymoma was approved for a Phase I trial. The first human patient was infused at the end of April 2023. The results of the first human trials, as described in 2024 by the New England Journal of Medicine, showed “dramatic and rapid” regression of glioblastoma.

In an exclusive briefing to Swim Across America participants, Dr. Bryan Choi, a neurosurgeon and neuro-oncologist at Massachusetts General Cancer Center, delivered an update on his research path.

From left, brain tumors, marked by red and green arrows, disappear a day after CAR-T immunotherapy treatment. From CNN.

The Swim Across America lab visit included not only highlights from on the ongoing Phase I trial, but also a few first-hand stories about the life-changing impacts of the new CAR-T cell therapy for one of the patients, who has chosen to share his story publicly.

Tom Fraser (Patient #2) has shared his story publicly with news outlets that include CNN and New York Magazine.

Tom Fraser, 72, (center, in the blue shirt) was treated with a single infusion of CAR-T cells. Two days later, an MRI showed a decrease in the tumor’s size by 18.5 percent. By day 69, the tumor had decreased by 60.7 percent, and the response was sustained for over 6 months. From The Harvard Gazette.

CAR T-cell therapy, a type of gene therapy that engineers a patient’s own T-cells (a type of white blood cells) to identify and attack cancer cells by way of their antigen markers, has shown promise in the treatment of blood cancers. The research team created dual antigen-targeting tandem CAR T (TanCART) cells to target heterogeneous solid tumors. Dr. Choi’s research shows that this type of therapy can also be manipulated to treat solid tumors like ependymoma.

At the suggestion of Dr. Howard Weinstein, Unit Chief of Pediatric Hematology/Oncology at Mass General for Children and long-time Swim Across America partner, Dr. Choi applied for a Swim Across America research grant through the internal competitive bid program at Mass General for Children. 

Dr. Choi recruiting the next generation of researchers, like SAA – Nantucket supporter, Braden Hussey.

Without the Swim Across America grant, Dr. Choi said, his research likely would have remained unfunded, and neither the FDA approval nor the Phase I Study approval, which is funded by industry investors, would have been possible.

Janel Jorgensen McArdle, Chief Operating Officer of Swim Across America, pointed out that Dr. Choi’s research falls in the “sweet spot” of the high risk, high reward research that Swim Across America is pursuing.

“This promising research aligned perfectly with the opportunities that Swim Across America seeks to support,” said McArdle. “We are so excited that SAA funding could help accelerate it to patient trials – and are thrilled to see the benefits to patients!”

Dr. Choi explained CAR-T cell therapy to the Swim Across America group on April 4, 2025.

After his highly informative presentation, Dr. Choi gave the Swim Across America group a private tour of his lab spaces, which were in the finishing stages of build-out when they toured two years ago. 

The group also got to visit the Ether Dome at Mass General, the surgical amphitheater where, in 1846, the first public surgery with anesthesia was performed.

It was an exciting visit for Swim Across America news and for all of the Swim Across America – Boston and Nantucket supporters who were present!

Swim Across America lab visit participants, pictured with Dr. Choi in the Ether Dome at Mass General, site of the first use of anesthesia in public surgery.

Swim Across America Grants  $900,000 Toward First-of-Its-Kind Gene Editing Innovation

Posted on Posted in #DefeatCancer, #MakingWavesToFightCancer, #SwimAcrossAmerica, beneficiaries, boston, Fairfield County, Grant, Making Waves With Hope, Messages of Hope, News, UncategorizedTagged , , , , , , , , Leave a comment

Revolutionary CRISPR Gene Editing and Other Cell and Gene Therapy Editing Takes Center Stage in Finding Ways to Effectively Treat Cancer

Swim Across America, the nonprofit funding innovative clinical trials and patient-centered programs for cancer, is proud to announce the award of two $450,000 grants to two of its beneficiaries, Alliance for Cancer Gene Therapy (ACGT) and Dana-Farber Cancer Institute, to support the work of novel gene and base editing techniques used in advanced cancer research, including targeted therapies, immunotherapies and cellular therapies. The two-year grants will specifically support the work of scientific investigators Joseph Fraietta, PhD, at the University of Pennsylvania through ACGT, and Pietro Genovese, PhD, at Dana-Farber Cancer Institute, for their work in groundbreaking cell and gene therapy cancer research. This financial support paves the way for more effective therapies across many cancer types including solid tumors, offering potential new hope for patients with hard to treat cancer types or limited treatment options.

“Gene editing, including CRISPR, are some of the most promising frontiers in cancer research allowing for advances in targeted therapies, immunotherapies, CAR-T cell therapy and early/minimal residual disease detection, diagnostics and cancer vaccines,” said Rob Butcher, CEO of Swim Across America. “These grants to Dr. Fraietta through ACGT, and Dr. Genovese at Dana-Farber, will help accelerate the advancement of potential gene-edited cancer treatments that could transform how we treat patients and their quality of life. Just as our previous funding has helped develop immunotherapy treatments that are saving lives today, we believe these pointed investments will help accelerate the next generation of cancer breakthroughs.”

Joseph Fraietta, PhD

Joseph Fraietta, PhD, through Swim Across America–Fairfield County beneficiary Alliance for Cancer Gene Therapy, is developing an innovative “off-the-shelf” cell therapy for aggressive cancers. His research uses a precise gene-editing tool called a “base editor” to create more effective CAR T cells that can target cancers with KRAS mutations, found in 20-25% of all cancers including lung, colon and pancreatic cancer. His team is also developing “micropharmacies” – immune cells engineered to release powerful cancer-fighting signals directly at tumor sites while minimizing side effects.

Pietro Genovese, PhD

Pietro Genovese, PhD, at Dana-Farber, is taking a revolutionary approach to treating acute myeloid leukemia (AML). Rather than targeting cancer cells directly, his team is creating “stealth” healthy blood cells engineered to survive cancer treatments while allowing the selective elimination of cancer cells. This innovative strategy could provide less toxic treatment options for AML and other blood cancers where traditional therapies often harm healthy cells along with cancerous ones.

“With the current funding landscape and resources potentially constrained, nonprofit organizations play a vital role in ensuring innovative cancer research moves forward,” said Evan Vosburgh, MD, Research and Grants committee chair for Swim Across America. “These targeted grants support precisely the kind of high-risk, high-reward research that could revolutionize cancer treatment, but might otherwise go unfunded. By supporting early-stage research in cell and gene therapy, we’re helping bridge critical funding gaps and accelerating the development of potentially life-saving treatments.”

Swim Across America has raised more than $100 million for cancer research since its founding in 1987 and has a strong track record of funding transformative research, including clinical trials that led to FDA-approved immunotherapy medicines Keytruda, Opdivo, Yervoy and Tecentriq. The organization was also a grant funder of Memorial Sloan Kettering’s landmark clinical trial that achieved a 100% success rate treating advanced rectal cancer patients with dostarlimab.

About Swim Across America Swim Across America hosts open water and pool swims in numerous communities nationwide, from Nantucket to under San Francisco’s Golden Gate Bridge. More than 150 Olympians support the organization, including Michael Phelps, Kate Douglass, Missy Franklin and Ryan Lochte. The organization supports more than 60 cancer research projects annually and has ten named Swim Across America Labs at major institutions nationwide. To learn more visit swimacrossamerica.org or follow on social media @SwimAcrossAmerica on Facebook and @SAASwim on Instagram.